“…Certain metrics were also found to be sensitive to differences across duct width, highlighting quantitative metrics with particular relevance for capturing the features of strictures and dilatation associated with patients with biliary disease [14]. Very recently, two studies conducted in 65 and 76 adult patients with PSC found that that MRCP+ metrics were significantly associated with biochemical prognostic scores and liver stiffness measurement (LSM) and suggested a role for refining risk stratification [15,16]. MRCP+ metrics have also shown utility in characterising disease, stratification and monitoring in paediatric patients [17,18] however, at present, there are no studies which have investigated the correlation between MRCP+ and clinical outcomes in PSC.…”