A quality of life study of patients with leprosy attending the dermatology OPD of a tertiary care center of Eastern India

Das, Nirmalya Kumar; De, Abhishek; Naskar, Biswanath; Sil, Abheek; Das, Sudip; Sarda, Aarti; Chatterjee, Gobinda

doi:10.4103/ijd.ijd_729_18

“…A majority of LL-type leprosy (58, 79.5%) were found to experience a large effect on the DLQI and were also statistically significant (p = 0.000 In our study, a leprosy reaction (type 1 and type 2) was present in 63 (38.41%) patients, was associated with a moderate effect in the DLQI, and was found to be statistically significant (p < 0.05) (Table 1). A similar observation was seen in a study by Nirmalya et al [6], in which a leprosy reaction (type 1 and type 2) was present in 51 (44.74%) patients and had a positive correlation with the DLQI score.…”

Section: Discussionsupporting

confidence: 89%

“…The mean ± SD of the age of the patients was 47.33 ± 17.47. In a study by Nirmalya et al [6], a majority of the patients (32; 28.07%) were in the age group of 41-50 years, and the mean age was 38.11 ± 12.16 years. In our study, age had a positive correlation and statistically significant impact in the DLQI (p < 0.05).…”

Section: Discussionmentioning

confidence: 94%

“…Leprosy-related QoL may be impacted by a number of variables, including the onset and progression of the disease, duration of the disease, social factors, and clinical variables, such type of leprosy, reactions, nerve involvement, disability grade, deformity, and systemic involvement. There are several studies on the assessment of QoL of patients with leprosy, in eastern India [6], Brazil [7], and China [8]. However, similar studies of QoL have not been done in south India.…”

Section: Introductionmentioning

confidence: 99%

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A study on the quality of life of patients with leprosy: A cross-sectional study

Kavana¹,

Manjunath2²

2023

Our Dermatol Online

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Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. If not detected early and treated adequately, it leads to disabilities and deformities, in turn leading to social stigma and discrimination. Hence, leprosy has an impact on the Quality of Life (QoL) of the affected. Materials and Methods: This study was conducted at the Dermatology Department and Leprosorium Hospital. A total of 164 leprosy patients were assessed for QoL with the Dermatology Life Quality Index (DLQI) questionnaire. Results: Among the total of 164 patients, leprosy had no effect on the QoL of 14 (8.54%) patients, a small effect on the QoL of 34 (20.73%) patients, a moderate effect on the QoL of 47 (28.66%) patients, a large effect on the QoL of 64 (39.02%) patients, and an extremely large effect on the QoL of 5 (3.05%) patients. Among the demographic variables, age, occupation, and socioeconomic status had an impact on the QoL of patients with leprosy. Conclusion: Leprosy is an ancient disease and continues to be the most feared due to deformities and the social stigma associated with it. The clinical spectrum, reactions, deformities, and disability have a profound impact on the QoL of patients with leprosy. Key words: Leprosy; DLQI questionnaire; Quality of life

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“…But in all study there is male predominance which supports our study. [12][13][14] In our study 20.83% patients has slide positive for AFB, it is higher in the study (38%) of Subhash Bishnoi et al but supported by the work of Giridhar, M & Arora et al (21%). 15,16 We have observed that most of the patients (53.34%) have lesions with bacteriological index 6+, and 26.27% patients have bacteriological index 1+.…”

Section: Discussionsupporting

confidence: 69%

Clinical and microbiological profile of Hansen’s diseases in a tertiary care centre of southwest Bihar

Kumar¹,

Kumar²

2020

IJCED

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Background: Leprosy or Hansen's disease is a slowly progressive infection caused by mycobacterium Lepra. It has been reported from Bihar that false positive diagnosis is a major issue and decline in false positive diagnosis is not statistically significant. Present study has been designed primarily to study the clinical presentation and microbiological profile of patients presenting with symptoms of Hansen disease and secondarily to know the smear positivity of patients with clinical manifestation of leprosy. Materials and Methods: After enrolment of patients a detail clinical examination was done and demographic information of patient was recorded on predesigned Performa. After taking consent from enrolled patients slit skin smear was obtained as pre standard protocol. Results: All patients below 20 years of age were slit smear staining smear negative for AFB. In our study 55(38.19%) patients with clinical manifestation were from 31 to 50 years of age among them 18(30 % of total AFB positive) was AFB positive. Among 30 patients with 16 (53.34%) patients have bacteriological index 6+ and 8 patients have bacteriological index 1+. Discussion and Conclusion: From present study we can conclude that there was male predominance and in most of the patients who were smear staining positive have bacteriological index more than 6+. Most common age group presented with clinical symptom and AFB positive were in 3 rd and 4 th decade of life. Hypopigmented macules were common presentation and AFB positive was most frequent in them.

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“…The disease had a large effect on the QoL of 64 (39.02%) patients, followed by a moderate effect in 47 (28.66%) patients. In a study conducted by Nirmalya et al [6], the disease had a very significant impact on 39 (34.21%) patients' QoL.…”

Section: Discussionmentioning

confidence: 94%

Untitled

2023

Our Dermatol Online

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Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. If not detected early and treated adequately, it leads to disabilities and deformities, in turn leading to social stigma and discrimination. Hence, leprosy has an impact on the Quality of Life (QoL) of the affected. Materials and Methods: This study was conducted at the Dermatology Department and Leprosorium Hospital. A total of 164 leprosy patients were assessed for QoL with the Dermatology Life Quality Index (DLQI) questionnaire. Results: Among the total of 164 patients, leprosy had no effect on the QoL of 14 (8.54%) patients, a small effect on the QoL of 34 (20.73%) patients, a moderate effect on the QoL of 47 (28.66%) patients, a large effect on the QoL of 64 (39.02%) patients, and an extremely large effect on the QoL of 5 (3.05%) patients. Among the demographic variables, age, occupation, and socioeconomic status had an impact on the QoL of patients with leprosy. Conclusion: Leprosy is an ancient disease and continues to be the most feared due to deformities and the social stigma associated with it. The clinical spectrum, reactions, deformities, and disability have a profound impact on the QoL of patients with leprosy.

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A quality of life study of patients with leprosy attending the dermatology OPD of a tertiary care center of Eastern India

Cited by 25 publications

References 16 publications

A study on the quality of life of patients with leprosy: A cross-sectional study

A study on the quality of life of patients with leprosy: A cross-sectional study

Clinical and microbiological profile of Hansen’s diseases in a tertiary care centre of southwest Bihar

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