A qualitative evaluation of the use of interventions to treat fatigue among cancer survivors: A healthcare provider’s view

Martin, Élise; Zingarello, Anna; Meglio, Antonio Di; Baciarello, Giulia; Matias, Margarida; Arvis, Johanna; Dumas, Agnès; Menvielle, Gwenn; Vaz-Luís, Inês

doi:10.1111/ecc.13370

Cited by 13 publications

(19 citation statements)

References 48 publications

(78 reference statements)

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“…This result also was similar to Martin et al, (2020) who carried out a study on "A qualitative evaluation of the use of interventions to treat fatigue among cancer survivors: A healthcare provider's view" and found that three quarters of the nurses were female.…”

Section: Demographic Datasupporting

confidence: 84%

Developing Nurses’ Performance Guidelines for Patients with Rectal Cancer Undergoing Radiotherapy

Khudary¹,

Abdelatief

Whman

et al. 2022

Egyptian Journal of Health Care

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Background: Rectal cancer is one of the most common forms of cancer and one of the top cancer killers. One of the modalities treatment is radiotherapy that causes fewer side effects as fatigue, skin reactions, gastrointestinal disturbance, rectal bleeding and bladder irritation. Nurses play important role in providing care for rectal cancer patients treated by radiotherapy (pre, during and post) exposure to radiation. Aim; This study aimed to develop nurses`performance guidelines for patient with rectal cancer undergoing radiotherapy. This aim was achieved through the following: Assessing knowledge and practices of nurses caring for patients with rectal cancer undergoing radiotherapy & developing nurses`performance guidelines for patients with rectal cancer undergoing radiotherapy. Design; A descriptive explorative design was utilized for conduction of this study. Setting; The study was conducted at the Radiotherapy Department and Outpatients' Clinics for oncology at Qena University Hospital. Study Subject; A convenient sample of all available nurses (N=30). Tools; I, self-administered questionnaire, II, an observational checklists Result; 63.33% of the studied nurses had satisfactory total knowledge regarding rectal cancer and 60% of them had unsatisfactory of total practices regarding care of patients with rectal cancer undergoing radiotherapy. Conclusion;Nearly more than half of the studied nurses had satisfactory total knowledge and also more than half of them had unsatisfactory total practices regarding rectal cancer. There was no a statistical significant correlation between studied nurses of total score of knowledge and total score of practices. Recommendations; on-going and regular in-service educational programs regarding evidence-based guidelines should include care of rectal cancer patients before, during and after radiotherapy.

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Section: Demographic Datasupporting

confidence: 84%

Developing Nurses’ Performance Guidelines for Patients with Rectal Cancer Undergoing Radiotherapy

Khudary¹,

Abdelatief

Whman

et al. 2022

Egyptian Journal of Health Care

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“…Cancer-related fatigue is one of the most prevalent symptoms patients suffer both during and after treatment [ 13 , 14 ], affecting 50–90% of all cases [ 14 , 15 , 16 ]. Fatigue appears regardless of age, sex, type of cancer, stage of disease, and treatment modality [ 15 , 17 , 18 ] and can become persistent, thereby limiting QoL and the activities of daily life for years [ 13 , 14 , 16 ]. Moreover, cancer-associated fatigue is unlike the exhaustion that most people experience as a result of their daily activities, inasmuch as it is not proportional to the level of effort and rest or sleep fail to remedy it [ 14 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Fatigue, Emotional Distress, and Illness Uncertainty in Patients with Metastatic Cancer: Results from the Prospective NEOETIC_SEOM Study

et al. 2022

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A cancer diagnosis can have a substantial impact on a patient’s mental health and quality of life. The aim of this study was to investigate the prevalence of fatigue, emotional distress, and uncertainty and examine the predictive value they have on the quality of life of advanced cancer patients. A prospective, multicenter study was conducted between February 2020 and May 2021 of individuals diagnosed with an advanced, unresectable neoplasm prior to initiating systemic antineoplastic treatment. Participants completed questionnaires to quantify fatigue, emotional distress, disease uncertainty, and quality of life. A linear regression analysis was performed to study the predictive QoL variables. The study population comprised 508 patients, 53.7% of whom were male and had a mean age of 54.9 years. The most common cancers were digestive (40.6%), bronchopulmonary (29.1%), and breast (8.5%); the most frequent histology was adenocarcinoma (63%); and most were stage IV (79.7%). More than half (55.7%) suffered fatigue, and 47.7% exhibited emotional distress; both were more prevalent among women. Fatigue, emotional distress, and disease uncertainty all correlate with diminished quality of life. Similarly, ECOG performance status and the demographic variables of age, sex, and comorbidities impacted quality of life. This patient sample displayed a high prevalence of fatigue and emotional distress, together with illness uncertainty, which are clearly linked to waning quality of life. To decrease the experience of fatigue and improve mental health treatment in cancer patients, interventions based on a biopsychosocial model must be intensified.

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“…Malignancy patients suffering from treatment and/or disease progression also suffer from cancer-related fatigue, which is a vexing issue. Management strategies for CRF are currently poorly understood, and the benefits of some pharmacological treatments and exercise-based interventions are relatively modest [18]. Although the etiology of CRF has been studied for nearly two decades, to date, there have been no large-scale, randomized, double-blind clinical trials to confirm the effectiveness of intervention methods.…”

Section: Discussionmentioning

confidence: 99%

Network Pharmacology/Metabolomics‐Based Validation of AMPK and PI3K/AKT Signaling Pathway as a Central Role of Shengqi Fuzheng Injection Regulation of Mitochondrial Dysfunction in Cancer‐Related Fatigue

Guo

Liu

Zheng

et al. 2021

Oxidative Medicine and Cellular Longevity

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Chinese herbal medicines have multiple targets and properties, and their use in multidisciplinary cancer therapies has consequently received increasing attention. Here, we have investigated the possible active ingredients associated with cancer-related fatigue (CRF) in the Shengqi Fuzheng Injection (SFI). In vitro cell models were used to measure the regulation effects of SFI on CRF. Metabolomic analysis was used to identify the potential genes and pathways in C2C12 mouse myoblasts treated with SFI, and the interaction of compounds and CRF targets was predicted using network pharmacology and molecular docking analyses. The putative pathways were further verified using immuno-blotting assays. The results showed that SFI significantly inhibited muscle cell apoptosis and increased the mitochondrial membrane potential of muscle cells. The network pharmacology analysis results identified 36 candidate compounds, and 244 potential targets were yielded by SFI, and they shared 10 key targets associated with cancer-related fatigue. According to the enrichment analysis and experimental validation, SFI might ameliorate muscle cell mitochondrial function by activating AMPK and inhibiting the PI3K/Akt signaling pathways, and the expression changes of mitochondrial metabolic enzymes MnSOD and apoptosis-associated proteins Bax and Bcl-2 were also triggered. The functions and mechanisms of SFI in anticancer-related fatigue were found here to be at least partly due to the targeting of the AMPK and PI3K/Akt signaling pathways, and this has highlighted new potential applications for network pharmacology when researching Chinese Medicines.

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A qualitative evaluation of the use of interventions to treat fatigue among cancer survivors: A healthcare provider’s view

Cited by 13 publications

References 48 publications

Developing Nurses’ Performance Guidelines for Patients with Rectal Cancer Undergoing Radiotherapy

Developing Nurses’ Performance Guidelines for Patients with Rectal Cancer Undergoing Radiotherapy

Fatigue, Emotional Distress, and Illness Uncertainty in Patients with Metastatic Cancer: Results from the Prospective NEOETIC_SEOM Study

Network Pharmacology/Metabolomics‐Based Validation of AMPK and PI3K/AKT Signaling Pathway as a Central Role of Shengqi Fuzheng Injection Regulation of Mitochondrial Dysfunction in Cancer‐Related Fatigue

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