“…One way to evaluate how well a particular stock flows is to determine the weight variation of a formulas at constant and preselected compressional force levels. In this manner the real effects of an added ingredient or modified manufacturing procedure can be definitely determined (5, 7 , 8 , 12,27). For example, during the development of a tablet prepared by a direct compaction process, the various formulations were compressed at the same force to determine the effects of both a dry binderdisintegrant and a flow promoting agent on the physical properties of the tablet.…”