A pulmonary vein atlas for radiotherapy planning

Walls, Gerard; McCann, Conor; Ball, Peter; Atkins, Katelyn M.; Mak, Raymond H.; Bedair, Ahmed; O’Hare, J.; McAleese, J.; Harrison, Claire; Tumelty, Karen A; Crockett, Cathryn; Black, Sarah-Louise; Nelson, C. Michael; O’Connor, John D.; Hounsell, Alan R.; McGarry, Conor K.; Butterworth, Karl T.; Cole, Aidan; Jain, Suneil; Hanna, Gerard G.

doi:10.1016/j.radonc.2023.109680

Cited by 6 publications

(1 citation statement)

References 37 publications

(53 reference statements)

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“…Generally, the occurrence of arrhythmias in cardiology is often centered around the pulmonary veins. A framework for radiotherapy planning was recently developed to define safe dosage limits for this specific structure [98] (Table 3). The analysis by Kim et al showed that 3 year AF rates could be stratified by several cutpoints: SA node D max ≥ 20 Gy vs. <20 Gy (10% vs. 1%, p < 0.001), RA D max ≥ 19.1 Gy vs. <19.1 Gy (8% vs. 1%, p = 0.01), and LA D max ≥ 55.8 Gy vs. <55.8 Gy (9% vs. 3%, p = 0.04) [95].…”

Section: Radiotherapymentioning

confidence: 99%

Cardiac Arrhythmias in Patients Treated for Lung Cancer: A Review

Hawryszko,

Sławiński,

Tomasik

et al. 2023

Cancers

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Cardio-oncology currently faces one of the greatest challenges in the field of health care. The main goal of this discipline is to ensure that patients treated for cancer do not suffer or die from cardiovascular disease. The number of studies on the mechanisms of heart injury during cancer treatment is constantly increasing. However, there is insufficient data on heart rhythm disorders that may result from this treatment. This issue seems to be particularly important in patients with lung cancer, in whom anticancer therapy, especially radiotherapy, may contribute to the onset of cardiac arrhythmias. The observed relationship between cardiac dosimetry and radiotherapy-induced cardiotoxicity in lung cancer treatment may explain the increased mortality from cardiovascular causes in patients after chest irradiation. Further research is essential to elucidate the role of cardiac arrhythmias in this context. Conversely, recent reports have highlighted the application of stereotactic arrhythmia radioablation (STAR) in the treatment of ventricular tachycardia. This review of available studies on the epidemiology, pathogenesis, diagnosis, and treatment of arrhythmias in patients treated for lung cancer aims to draw attention to the need for regular cardiological monitoring in this group of patients. Improving cardiac care for patients with lung cancer has the potential to enhance their overall therapeutic outcomes.

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Section: Radiotherapymentioning

confidence: 99%