“…A low-cost signature that included C-reactive protein as an indicator of systemic inflammation, PTX3 as a correlate of tissue reaction, and lactate dehydrogenase as an indicator of cell and tissue damage was found to correlate with the severity of lesions on computed tomography and subsequent disease progression in patients with paucisymptomatic Covid-19. 18 Integration of low-tech, low-cost measurement of selected acute-phase proteins with molecular signatures may pave the way to the development of tools allowing more patient-tailored early approaches.…”