A psychometric assessment of the St. George’s respiratory questionnaire in patients with COPD using rasch model analysis

Lo, Chyi; Liang, Wen Miin; Hang, Liang Wen; Wu, Tai Chin; Chang, Yu-Jun; Chang, Chih Hung

doi:10.1186/s12955-015-0320-7

Cited by 21 publications

(21 citation statements)

References 35 publications

(63 reference statements)

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“…The main issue was the inclusion of two items in the scoring (“Sitting or lying still making feel breathless” and “Playing sports or game making feel breathless”). This finding was consistent with previous findings reported in the literature, 12 , 22 that led to the creation of the SGRQ-C. 12 The examination of cross-cultural performances of the SGRQ “Activity” items showed a great variability in the responses to these items in different global regions.…”

Section: Discussionsupporting

confidence: 91%

<p>Is the St. George’s Respiratory Questionnaire an Appropriate Measure of Symptom Severity and Activity Limitations for Clinical Trials in COPD? Analysis of Pooled Data from Five Randomized Clinical Trials</p>

Loubert¹,

Regnault²,

Meunier³

et al. 2020

COPD

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Purpose The objective of this study was to examine the psychometric properties of the St. George’s Respiratory Questionnaire (SGRQ) in patients with chronic obstructive pulmonary disease (COPD) using Rasch measurement theory (RMT) analyses. Materials and Methods RMT analysis was conducted on the baseline SGRQ data from five multi-national, Phase III randomized trials investigating a fixed-dose combination of a long-acting β2-agonist and a long-acting muscarinic antagonist in COPD patients. Analysis was performed for the SGRQ “Symptoms” and “Activity” domains. An exploratory analysis was also conducted using the different specific symptoms as defined in the reconceptualization of the SGRQ “Symptoms” domain. Differential item functioning (DIF) analysis was performed for geographical regions on the “Activity” domain, in order to explore cross-cultural validity of the SGRQ. Results Overall, the SGRQ “Activity” domain showed good measurement property, but two items (“Sitting or lying still making feel breathless” and “Playing sports or game making feel breathless”) showed very high fit residuals. The SGRQ “Symptoms” domain demonstrated good targeting; however, two items showed disordered thresholds (“Coughed” and “Brought up phlegm”). In an exploratory RMT analysis, measures for “Cough and Sputum”, “Breathing difficulties” or “Wheezing attacks” showed unsatisfactory measurement properties with poor reliability (person separation index = 0.35, 0.66 and 0.16, respectively) and targeting issues. The examination of cross-cultural performances of the SGRQ “Activity” items showed a great variability in the responses to these items in different global regions. Conclusion Our results indicated that SGRQ may not be an appropriate instrument to measure symptom severity or activity limitations in patients with COPD. Hence, there is a need to develop other relevant PRO instruments that can be used in conjunction with SGRQ to provide a holistic assessment of the health status of COPD patients in clinical research.

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Section: Discussionsupporting

confidence: 91%

<p>Is the St. George’s Respiratory Questionnaire an Appropriate Measure of Symptom Severity and Activity Limitations for Clinical Trials in COPD? Analysis of Pooled Data from Five Randomized Clinical Trials</p>

Loubert¹,

Regnault²,

Meunier³

et al. 2020

COPD

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“…Kuesioner ini dapat digunakan pada pasien dengan usia 17 hingga 80 tahun dan merupakan kuesioner spesifik untuk pasien asma dan PPOK 5 . Validitas SGRQ telah dilakukan di beberapa negara terhaap berbagai penyakit pernafasan antara lain PPOK, chronic pulmonary aspergillosis dan Idiopathic Cyctic fibrosis [6][7][8] . Di Indonesia juga sudah pernah dilakukan penerjemahan dan validasi kuesioner SGRQ sebagai alat pengumpul data untuk mengukur kualitas hidup pada pasien Tuberkolosis (TB) dan hasilnya SGRQ valid dan reliabel untuk mengukur kualitas hidup pada pasien TB 9 .…”

Section: Penahuluanunclassified

Validation of St. George's Respiratory Questionnaire (SGRQ) in Chronic Obstructive Pulmonary Disease (COPD) at Respira Lung Hospital Yogyakarta

Pratiwi

Perwitasari

2017

J. Manaj. dan Pelayanan Farm.

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ABSTRAKPrevalensi Penyakit Paru Obstruktif Kronis (PPOK) di Indonesia semakin meningkat. Diperkirakan pada tahun 2020 PPOK akan menjadi penyebab kematian ketiga di dunia. Salah satu tujuan terapi dari PPOK sebagai penyakit kronik adalah meningkatkan kualitas hidup pasien. Penelitian ini bertujuan untuk memvalidasi kuesioner St. George's Respiratory Questionnaire (SGRQ) versi Indonesia sebagai instrumen untuk mengukur kualitas hidup pasien PPOK di RS Paru Respira, Yogyakarta. Penelitian ini menggunakan rancangan potong lintang yang dilakukan di RS Paru Respira, Yogyakarta dari bulan Juni-Juli 2016. Pengumpulan data dilakukan dengan menggunakan rekam medik pasien dan wawancara secara langsung kepada pasien menggunakan kuesioner SGRQ. Subyek penelitian yang digunakan adalah pasien PPOK yang berusia 17-80 tahun. Analisis statistik dilakukan untuk mengetahui validitas konstruk, known-group dan reliabilitas kuesioner. Sejumlah 41 responden berpartisipasi dalam penelitian ini. Kuesioner SgRQ versi Indonesia memenuhi kriteria reliabilitas dengan nilai Cronbach alpha mencapai > 0.7 untuk domain gejala, aktivitas dan dampak. Terdapat 17 pertanyaan dan 10 pertanyaan pada ketiga domain yang tidak memenuhi validitas konvergen dan diskriminan. Perbedaan bermakna muncul pada domain gejala berdasar kelompok umur 17-48 dan 49-80 tahun (p<.05). Kuesioner The SGRQ versi Indonesia belum memenuhi kriteria validitas namun masih memenuhi kriteria reliabel. Kata kunci: SGRQ, Indonesia, PPOK, validitas ABSTRACTThe prevalence of COPD in Indonesia is getting increase. Over the world, COPD is predicted to be the third cause of death in 2020. As the chronic disease, quality of life became one of the outcome treatments of COPD. This research was aimed to validate Indonesian version of St. George's Respiratory Questionnaire (SGRQ) Indonesian. This study used cross sectional design approach from June to July 2016, conducted in Respira Lung Hospital, Yogyakarta. Data was collected from medical record and direct interviews to patients using SGRQ. An inclusion criterion was adult patients with COPD. Some statistical tests were performed to analyze construct validity, known group validity and reliability of Indonesian version of SGRQ. We recruited 41 respondents. The SGRQ meet reliability criteria with the value of Cronbach alpha are > 0.7 for symptom, activity and impact domains. There are 17 questions and 10 questions in symptom, activity and impact domains which do not meet convergent and discriminant validity. The significant difference is found in symptom domain for the 17-48 and 49-80 year age. The SGRQ Indonesian version is not valid enough to be used in clinical practice but still reliable.

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“…Psychometric differences between the SGRQ domains are recognized in the literature, and it has been suggested that the SGRQ (Activity) and SGRQ (Symptoms) domains have greater accuracy [37]. In present study, depression was identified using the MINI diagnostic tool, where the influence from the patient’s subjective evaluation of their health is mitigated.…”

Section: Discussionmentioning

confidence: 93%

Depression diagnosed by the mini international neuropsychiatric interview plus (MINI) in patients with chronic obstructive pulmonary disease: relationship with functional capacity and quality of life

Orlandi

Pinho

Rocha³

et al. 2016

BMC Res Notes

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BackgroundThe prevalence of depression in patients with chronic obstructive pulmonary disease (COPD) is associated with a worsening of prognosis. Most studies classify COPD patients as depressive or non-depressive based on symptoms, rather than on a diagnosis using specific tools. Thus, the aim of this study was to determine the impact of depression, as diagnosed by the Mini International Neuropsychiatric Interview Plus (MINI), on functional capacity estimated by the 6-minute walk test (6MWT) and unsupported upper-limb exercise test, and quality of life estimated by Saint George’s Respiratory Questionnaire (SGRQ), among patients with COPD.ResultsUsing the MINI as a diagnostic tool, 22.2 % of all patients (6.6 % of all men and 41.6 % of all women) were diagnosed with depression. No significant differences were found between depressive and non-depressive patients with regard to anthropometric measurements, lung function, functional capacity, or quality of life variables. The best models for the dependent variables representing functional capacity and quality of life revealed that the covariates SGRQTOTAL and gender (R2 = 16.7 %) were significant in explaining the response variable for functional capacity of the upper limbs. Results also showed that age, monthly income, insomnia, and the results of a 6MWT were significant in explaining overall quality of life (R2 = 46 %), and that the percentage of the predicted forced expiratory volume in the first second post-bronchodilator and gender were significant in explaining walking distance (R2 = 22 %). Depression, as diagnosed by the MINI, was not significant in explaining any of the dependent variables.ConclusionsDespite a high prevalence of depression in COPD patients, especially in women, depression, as diagnosed by the MINI, was not correlated with functional capacity tests or quality of life in patients with moderate to very severe COPD in the present study. This suggests that depression identified by this diagnostic test may be more accurate than depression diagnosed by tests that evaluate symptoms, as they may be influenced by the perceptions of the patient in relation to their health.

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A psychometric assessment of the St. George’s respiratory questionnaire in patients with COPD using rasch model analysis

Cited by 21 publications

References 35 publications

<p>Is the St. George’s Respiratory Questionnaire an Appropriate Measure of Symptom Severity and Activity Limitations for Clinical Trials in COPD? Analysis of Pooled Data from Five Randomized Clinical Trials</p>

<p>Is the St. George’s Respiratory Questionnaire an Appropriate Measure of Symptom Severity and Activity Limitations for Clinical Trials in COPD? Analysis of Pooled Data from Five Randomized Clinical Trials</p>

Validation of St. George's Respiratory Questionnaire (SGRQ) in Chronic Obstructive Pulmonary Disease (COPD) at Respira Lung Hospital Yogyakarta

Depression diagnosed by the mini international neuropsychiatric interview plus (MINI) in patients with chronic obstructive pulmonary disease: relationship with functional capacity and quality of life

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