A pseudoaneurysm within a subperiosteal collection in a patient with sickle cell disease

Abstract

Sickle cell disease involves long bones in the form of infection or subperiosteal collections. Rare pseudoaneurysm/aneurysm formation is also known to occur in the intracranial and visceral territories. We report a small subperiosteal pseudoaneurysm that developed within a subperiosteal abscess in the tibia in a patient with sickle cell disease. This case adds to the known spectrum of musculoskeletal abnormalities resulting from this condition.

A Rare Case of a Sickle Cell Patient With Post Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis and Pseudoaneurysm Formation: An Association Worth Exploring

“…The vasculopathy from our patient's sickle cell disease likely caused an already compromised vessel wall at the IPDA, in addition to an active sickle cell crisis denoted by LDH two times his baseline, and sickled cells are seen on the manual differential, direct trauma during the ERCP, mechanical irritation from the stents, and post-procedure pancreatitis, all could have contributed to the formation of a pseudoaneurysm [15]. Similar phenomena of two patients with sickle cell disease and pseudoaneurysms have been reported in the literature: one within a tibial abscess and another within the IPDA as well [16,17]. This rare and recurrent association will need to be further explored as a potential risk factor for pseudoaneurysm formation in the sickle cell patient population.…”