A prospective study to determine association between serum uric acid and diabetic retinopathy

Abstract

To explore the role of serum uric acid (SUA) concentration in diabetic retinopathy (DR) for patients with type 2 diabetes mellitus (T2DM). Methods: The present prospective observational study was conducted in department of Ophthalmology at Chattrapati Shivaji Subharti hospital from December 2019 to November 2020. The diabetic patients were assigned to one of the following groups based on presence and severity of diabetic retinopathy with the help of fundus photographs and/or fundus fluorescein angiography. Results: On correlation analysis, it was found that there is significant relationship between Serum Uric Acid and fundus grading of diabetic retinopathy as r=.310 and p <0.016. On regression analysis, the model summary states that 9.6% variation can be explained by serum uric acid on fundus grade as R square =.096 with P=.016 and hence regression model is significant.