A Prospective Study on Haemotological Profile of Sickle Disease
Kinjal G. Patel,
Chintu Chaudhari
Abstract:Background: Sickle cell disease (SCD) refers to a category of inherited hemoglobin (Hb) disorders. The pathophysiology of sickle Hb (HbS) variant emerges from the polymerization of the ensuing HbS variant, which triggers a chain of erythrocyte alterations and the disorder is known to be caused by a single-nucleotide substitution at position 6 of the globin gene. Both acute and chronic sequelae cause significant morbidity in people with sickle cell anemia (SCA). Methods: This prospective cross-sectional study w… Show more
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