A prospective study on adverse drug reactions reported in a tertiary referral hospital

Mayathevar, Brahadeesh; Thiyagarajan, Dhivya; Soundararajan, Thamilarasi; Vallish, B N; Rizwan, Sadia

doi:10.18203/2319-2003.ijbcp20164406

Cited by 2 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results were contrast to study on gender related differences by Prasad et al 7 Comparing the route of administration, no of reactions occurred with the oral 62% followed by IV 31% and others (SC, IM, INH, SL, LA) 6.36%. Which was in congruence with study proposed by Dhivya et al 8 The most occurred reaction is Hyponatremia 22 (7%), followed by hypokalaemia 18 (5%) and diarrhoea 13 (4% was the fourth highest in our study, followed by nervous system and psychiatric disorders. 12 It is because of difference in prevalent causative drugs that are involved (acid related, anti-inflammatory and analgesics) in study.…”

Section: Resultssupporting

confidence: 93%

Analysis of voluntary reported adverse drug reactions in a tertiary care hospital

Sivakumar¹,

D.²,

Devashree³

et al. 2023

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

Background: Adverse drug reactions are the major cause for increased hospital stay and it increases the economic burden of the patients. Reporting of ADR helps in signal generation and to ensure safe use of a drug. Present study was conducted to analyse the ADR reporting pattern and completeness of the ADR forms. Methods: This was a retrospective study conducted for 6 months in a tertiary care hospital. A total of 330 ADR forms were analysed and completeness of ADR forms were assessed. Results: A total of 330 ADRs were reported. 46% ADRs were reported in 2018, 23% in 2019, 11% in 2020, 8.9% in 2021 and 10.7% in 2022. 177 (53%) were males and 153 (47%) were females. Most occurred reaction was Hyponatremia 22 (6%), followed by Hypokalaemia 18 (5%). Neuropsychiatry cases were 62 (18.78%), Urinary system cases were 45 (13.63%). 122 (88%) patients were taking concomitant drugs whereas only 17 (12%) patients were not taking. Above 80% completeness were seen in 155 (46.96%) forms. Above 70% completeness in 292 (88.68%) forms. Conclusions: ADRs occurrence was high in male compared to female. Most of the ADRs affected Neuropsychiatry followed by Urinary system. Antimicrobials are responsible for majorly reported ADRs followed by cephalosporins (17.6%) and Penicillin (11.76%). Overall completeness of reported ADR form was 80%, 67.87% of forms were not adequately filled with mandatory fields.

show abstract

Section: Resultssupporting

confidence: 93%

Analysis of voluntary reported adverse drug reactions in a tertiary care hospital

Sivakumar¹,

D.²,

Devashree³

et al. 2023

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

show abstract

“…Out of 82 reported ADRs 56 (68%), the oral route of administration was followed by intravenous and intra-arterial. About 66.7% and 80% of ADRs were occurred due to the oral route of administration in Mayathevar B et al, 13 and Misra D et al, 14 study respectively. Other studies showed that the oral route was higher when compared to parenteral and topical.…”

Section: Fig 3: Causality Assessment As Per the Umc-who Scalementioning

confidence: 90%

Untitled

2022

IJPSR

View full text Add to dashboard Cite

Adverse drug reactions (ADRs) cause considerable morbidity and mortality worldwide. The pharmacovigilance activities continuously update about the adverse reactions related to medications and provide information regarding the nature and severity of ADRs. The study aims to assess the causality assessment of ADRs among patients in a tertiary care hospital. A prospective observational study was conducted in a tertiary care hospital for eight months, from September 2019 to April 2020. A total of 87 patients among 79 patients had reported with 82 ADRs. Based on the gender, males were higher than females. 40 ADRs were reported between 61-80 years of age. 27 ADR reported by diuretic users, and 15 were caused by furosemide users. 32 ADRs were endocrine damage. Causality assessment has been performed using the world health organization-Uppsala monitoring center, 63 possible followed by 13 probable/ likely. In the majority, 54 suspected ADRs were withdrawn. Based on the study duration, 40 were recovering stages. Monitoring and reporting of ADR among healthcare professionals should be encouraged as well as creating awareness of ADR reporting among patients can improve quality of life and prevent hospitalization.

show abstract

A prospective study on adverse drug reactions reported in a tertiary referral hospital

Cited by 2 publications

References 1 publication

Analysis of voluntary reported adverse drug reactions in a tertiary care hospital

Analysis of voluntary reported adverse drug reactions in a tertiary care hospital

Untitled

Contact Info

Product

Resources

About