A Prospective Study of the Clinical Characteristics of Patients With Herpes Simplex and Varicella Zoster Keratitis, Presenting to a New Zealand Emergency Eye Clinic

McDonald, Elissa M; Patel, Dipika V.; McGhee, Charles N J

doi:10.1097/ico.0000000000000338

Cited by 14 publications

(14 citation statements)

References 30 publications

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“…Among studies that examined the effect of patient characteristics on outcome, neither age nor gender influenced the rate of corneal healing during antiviral therapy for HSV epithelial keratitis (de Koning 1982; de Koning 1983; Jackson 1984; McCulley 1982; van Bijsterveld 1980; van Bijsterveld 1989). Observational studies have suggested that some ethnic groups may be susceptible to recurrent HSV epithelial keratitis (McDonald 2015; Wilhelmus 1996a), but ethnicity was not significantly associated with recurrence in a cohort followed for 18 months (HEDS Group 2001). Insufficient information was available to examine age, gender, or ethnicity as possible effect modifiers in this review.…”

Section: Discussionmentioning

confidence: 99%

“…• Intravitreal corticosteroid (Gulkilik 2007;Shtein 2007) Other immunosuppressive treatment • Topical ophthalmic calcineurin inhibitor (Field 1995;Joseph 2005) • Inhaled corticosteroid (Garcia-Medina 2011;McDonald 2015) • Systemic immunosuppressants following organ or bone marrow transplantation (Hayashi 2008;Kremer 1991;Ng 1998) • Systemic immunosuppressants given for autoimmune disorders (Larrañaga Fragoso 2015)…”

Section: Differential Diagnosismentioning

confidence: 99%

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Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis

Wilhelmus

2015

Cochrane Database of Systematic Reviews

106

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Background-Eye disease due to herpes simplex virus (HSV) commonly presents as epithelial keratitis which, though usually self-limiting, may persist or progress without treatment.Objectives-To compare the relative effectiveness of antiviral agents, interferon, and corneal debridement in the treatment of HSV epithelial keratitis. Search methods-We searched CENTRAL (which contains the Cochrane Eyes and Vision

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Section: Discussionmentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis

Wilhelmus

2015

Cochrane Database of Systematic Reviews

106

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“…In particular, HZ ophthalmicus (HZO) arising from the ophthalmic division accounts for 5% to 25% of HZ cases in Asia-Pacific countries [11, 15, 17, 22, 30, 102, 104, 136, 154, 340, 354] (Table 5). The majority of cases, especially those accompanied by nose eruptions (Hutchinson's sign) [372–375], are complicated by secondary inflammation such as conjunctivitis, keratitis [376–378], scleritis, and uveitis/iridocyclitis [372–374, 379–381]. Such complications can cause glaucoma and are potentially blinding, especially if not treated promptly [379, 382].…”

Section: Complicating Presentations and Disease Associationsmentioning

confidence: 99%

Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific

et al. 2017

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BackgroundHerpes zoster (HZ) is a prevalent viral disease that inflicts substantial morbidity and associated healthcare and socioeconomic burdens. Current treatments are not fully effective, especially among the most vulnerable patients. Although widely recommended, vaccination against HZ is not routine; barriers in Asia-Pacific include long-standing neglect of adult immunisation and sparse local data. To address knowledge gaps, raise awareness, and disseminate best practice, we reviewed recent data and guidelines on HZ from the Asia-Pacific region.MethodsWe searched PubMed, Scopus, and World Health Organization databases for articles about HZ published from 1994 to 2014 by authors from Australia, China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, New Zealand, the Philippines, Singapore, Taiwan, Thailand, and Vietnam. We selected articles about epidemiology, burden, complications, comorbidities, management, prevention, and recommendations/guidelines. Internet searches retrieved additional HZ immunisation guidelines.ResultsFrom 4007 retrieved articles, we screened-out 1501 duplicates and excluded 1264 extraneous articles, leaving 1242 unique articles. We found guidelines on adult immunisation from Australia, India, Indonesia, Malaysia, New Zealand, the Philippines, South Korea, and Thailand.HZ epidemiology in Asia-Pacific is similar to elsewhere; incidence rises with age and peaks at around 70 years – lifetime risk is approximately one-third. Average incidence of 3–10/1000 person-years is rising at around 5% per year. The principal risk factors are immunosenescence and immunosuppression. HZ almost always causes pain, and post-herpetic neuralgia is its most common complication. Half or more of hospitalised HZ patients have post-herpetic neuralgia, secondary infections, or inflammatory sequelae that are occasionally fatal. These disease burdens severely diminish patients’ quality of life and incur heavy healthcare utilisation.ConclusionsSeveral countries have abundant data on HZ, but others, especially in South-East Asia, very few. However, Asia-Pacific countries generally lack data on HZ vaccine safety, efficacy and cost-effectiveness. Physicians treating HZ and its complications in Asia-Pacific face familiar challenges but, with a vast aged population, Asia bears a unique and growing burden of disease. Given the strong rationale for prevention, most adult immunisation guidelines include HZ vaccine, yet it remains underused. We urge all stakeholders to give higher priority to adult immunisation in general and HZ in particular.Electronic supplementary materialThe online version of this article (doi:10.1186/s12879-017-2198-y) contains supplementary material, which is available to authorized users.

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“…M aori are overrepresented in herpes simplex keratitis, accounting for an estimated 22% of cases in the Auckland region. 50 Of the total presumed microbial keratitis cases among M aori, herpes simplex accounts for a significant proportion (71%). The diagnosis of herpes simplex keratitis increases almost fivefold among M aori compared to non-M aori.…”

Section: Herpes Simplex Keratitis and Varicella Zoster Keratitismentioning

confidence: 99%

Te hauora karu o te iwi Māori: A comprehensive review of Māori eye health in Aotearoa/New Zealand

Rapata

Cunningham

Harwood

et al. 2023

Clinical Exper Ophthalmology

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This article provides a summary of available data on Māori ocular health, highlighting significant disparities between Māori and non‐Māori populations. Māori are more likely to develop diabetes, sight‐threatening retinopathy and keratoconus, and present for cataract surgery earlier with more advanced disease. Limited data exists for macular degeneration and glaucoma, but there is some suggestion that Māori may have lower prevalence rates. The article emphasises the urgent need for robust national data on Māori ocular health to enable targeted interventions and funding allocation. Achieving equity for Māori in all aspects of health, including ocular health, requires concerted efforts from all stakeholders.

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A Prospective Study of the Clinical Characteristics of Patients With Herpes Simplex and Varicella Zoster Keratitis, Presenting to a New Zealand Emergency Eye Clinic

Cited by 14 publications

References 30 publications

Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis

Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis

Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific

Te hauora karu o te iwi Māori: A comprehensive review of Māori eye health in Aotearoa/New Zealand

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