A Prospective Study of Renal Stone Recurrences

Ljunghall, Sverker; Danielson, Bo G.

doi:10.1111/j.1464-410x.1984.tb05346.x

Cited by 157 publications

(79 citation statements)

References 9 publications

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“…The current study shows that success rate had ahigher range regarding upper calyceal and pelvic stones (70%-90%) compared to 50%-70% success rate for the lower calyceal stones, this finding is similar to data of some previously published studies [2,[5][6][7].…”

Section: Discussionsupporting

confidence: 81%

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Success Rate of Stone Recurrence after Extracorporeal Shockwave Lithotripsy and Factors affecting Success of Treatment among Egyptian Patients

Gadalla¹

2016

Med Surg Urol

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Objectives: To evaluate the factors that affect the success rate of ESWL for treatment of renal stones and to estimate the prevalence of stone recurrence during a 1-year period. Materials and Methods:During the period of January, 2010 and December, 2010, prospective study of 142 subjects with single or multiple renal stones (<30 mm, largest diameter) undergone ESWL monotherapyby Siemens-LITHOSKOP lithotriptor. The results of treatment were assessedafter a follow-up period of 3 months. Treatment success was a complete clearance of the stones or presence of insignificantresidual fragments<4 millimeters. Correlation of the success rate with the characteristics of the subjects, conditionsof the urinary tract and features of the stone was done.Results: During the 3-months follow-up period, the success rate was 111/142 (78%). Re-treatment was needed in 75 patients (52.8%). Post-treatment procedures were done in 12 subjects (8.4%). Post-ESWL complications were observed in 5 subjects (3.5%). Out of 10 prognosticfactors studied, 5 had a powerful influence on the success rate, which are: renal morphology, presence of congenital anomalies, size of stone, site of stone and treated stones number. Other factors including age, sex, nationality, stonenature (de novo or recurrent) and ureteric stenting had no significant impact on the success rate. Conclusions:Prediction of success of treatment with ESWL and the recurrence depends and may be predicted by renal morphology, presence of congenital anomalies, size of stone, site of stone and treated stones number.

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Section: Discussionsupporting

confidence: 81%

“…In addition, retained stone fragments following this therapy may reform or compose a nucleus for another stone formation, hence causes a high rate of stone growth [2][3][4][5]. The patient's chances of first episode recurrent stone formation range between 27% and 50% [6,7].…”

Section: Introductionmentioning

confidence: 99%

Success Rate of Stone Recurrence after Extracorporeal Shockwave Lithotripsy and Factors affecting Success of Treatment among Egyptian Patients

Gadalla¹

2016

Med Surg Urol

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“…Group VI: Curative treated -Received drinking water containing EG and AC ad libitum from 1-15 th day and ERT 0.5 g/kg, orally from [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] th day. Group VII: Curative treated -Received drinking water containing EG and AC ad libitum from 1-15 th day and ERT 1.0 g/kg, orally from [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] th day.…”

Section: Study Protocolmentioning

confidence: 99%

“…Group V: Curative control -Received drinking water containing EG and AC ad libitum from 1-15 th day and distilled water 10 ml/kg, orally from [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] th day. Group VI: Curative treated -Received drinking water containing EG and AC ad libitum from 1-15 th day and ERT 0.5 g/kg, orally from [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] th day. Group VII: Curative treated -Received drinking water containing EG and AC ad libitum from 1-15 th day and ERT 1.0 g/kg, orally from [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] th day.…”

Section: Study Protocolmentioning

confidence: 99%

Evaluation of <I>Ruellia tuberosa</I> L. for Antiurolithiatic and Antioxidant Activities in Rats

Sailaja¹,

Bharathi²,

Prasad³

2010

Journal of Pharmaceutical Research

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The roots of Ruellia tuberosa L. are recommended for kidney stone disorders in the Indian traditional system of medicine. Ethanolic extract of R. tuberosa roots was evaluated for antiurolithiatic activity against 0.75% v/v ethylene glycol and 2% w/v ammonium chloride induced calcium oxalate urolithiasis and for antioxidant activity against hyperoxaluria induced oxidative stress in male albino rats. Ethylene glycol and ammonium chloride administration increased the deposition of calcium and oxalate in the kidneys, urinary excretion of calcium, oxalate and creatinine in the preventive and curative control rats. In these groups, increased levels of malondialdehyde and depleted levels of antioxidant enzymes, reduced glutathione and catalase were observed. On treatment with the extract, a significant reduction in the deposition of calcium, oxalate and also urinary excretion of calcium, oxalate and creatinine was observed, indicating its antiurolithiatic effect. The extract administration also decreased the extent of lipid peroxidation and enhanced the levels of antioxidant enzymes in the kidneys of urolithic rats, reflecting its antioxidant efficacy against hyperoxaluria induced renal oxidative stress. Results of the present study support the traditional claim of R. tuberosa roots in treating renal calculi.

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“…In addition, retained stone fragments following those therapies may reaggregate or constitute a nucleus for new stone formation, thereby causing a high rate of stone growth (1)(2)(3)(4). The patient's chances of first episode recurrent stone formation range between 27% and 50% (5,6). Medical treatment should therefore be considered following these interventions, in order to prevent further secondary treatments and hospitalizations.…”

mentioning

confidence: 99%

Alkaline citrate reduces stone recurrence and regrowth after shockwave lithotripsy and percutaneous nephrolithotomy

et al. 2011

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Objective: To evaluate the preventive effects of alkaline citrate on stone recurrence as well as stone growth post-ESWL or PCNL in patients with calcium-containing stones. Materials and Methods: A total of 76 patients with calcium calculi who were stone-free or had residual stones less than 4 mm following ESWL and PCNL were enrolled. All patients were independently randomized into two groups. The treated group (N = 39) was given 81 mEq per day of oral potassium-sodium citrate (27 mEq three times a day), and the untreated group (N = 37) serving as controls. Blood, twenty-four hour urine analysis, and plain KUB were measured and compared at the baseline and after 12 months. Results: At baseline, hypocitraturia was found in 20 of 39 patients (46.05%) of Group I and 15 of 37 patients (40.5%) of Group II. At 12 months, hypocitraturia was found in 3 of 39 (7.69%) and 14 of 37 (37.83%) of Group I and Group II, respectively (p = 0.007). At the 12 month follow-up, of the stone-free group, 92.3% of the treated group and 57.7% of the control group were still stone free. Of the residual stone group, 30.8% and 9.1 % of treated and control group were stone-free, respectively. The increased stone size found in 7.7% and 54.5% of treated and control groups, respectively. Conclusion: Sodium-potassium citrate provides positive effects on stone-forming activities in calcium stone patients suffering from urolithiasis following treatment with ESWL and PCNL procedures at the 12-month follow-up. With the advantage of high efficiency and low morbidity rates, extracorporeal shock wave lithotripsy (ESWL) has become the therapy of choice for small renal stones. Percutaneous nephrolithotomy (PCNL) is also becoming the therapy of choice for large renal stones due to the less invasive procedure as compared to open nephrolithotomy. These therapies provide good results, associated with an acceptable rate of complications, but unfortunately they do not change the underlying metabolic abnormality. Stone recurrence is usually found after either treatment, even in those with a stone-free post-therapy status. In addition, retained stone fragments following those therapies may reaggregate or constitute a nucleus for new stone formation, thereby causing a high rate of stone growth (1-4). The patient's chances of first episode recurrent stone formation range between 27% and 50% (5,6). Medical treatment should therefore be considered following these interventions, in order to prevent further secondary treatments and hospitalizations. Among the metabolic disorders usually found in recurrent stone forming patients, hypocitraturia Clinical Urology

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A Prospective Study of Renal Stone Recurrences

Cited by 157 publications

References 9 publications

Success Rate of Stone Recurrence after Extracorporeal Shockwave Lithotripsy and Factors affecting Success of Treatment among Egyptian Patients

Success Rate of Stone Recurrence after Extracorporeal Shockwave Lithotripsy and Factors affecting Success of Treatment among Egyptian Patients

Evaluation of <I>Ruellia tuberosa</I> L. for Antiurolithiatic and Antioxidant Activities in Rats

Alkaline citrate reduces stone recurrence and regrowth after shockwave lithotripsy and percutaneous nephrolithotomy

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