A Prospective Study of Prescribing Pattern of Antihypertensive Drugs in Tertiary Care Hospital, Bangalore

Abstract

BACKGROUND: Hypertension is the most common cardiovascular disease. Sustained arterial hypertension damages blood vessels in kidney, heart, brain and leads to an increased incidence of renal failure, coronary disease, heart failure and stroke. Effective pharmacologic lowering of blood pressure has been shown to prevent damage to blood vessel and so substantially reduce morbidity and mortality rates.AIM: This drug utilization study was intended to find out the preferred drug group prescribed either alone or in combinations and their adherence to the JNC7 guidelines. Furthermore the prescription variations as regards to the age and concomitant illness were also analyzed. METHODS AND MATERIAL: Drug utilization data were analyzed after getting the patient's particulars regarding age, sex, drugs, concomitant illness etc. in the proforma. RESULTS: After analysis, it was found that most frequently prescribed antihypertensive drugs were ARBs (58%), CCBs (50%), Beta blockers(15%), Diuretics (14%). 68% received monotherapy while remaining 32% received combination therapy. CONCLUSION: The prescription pattern was found to be partly in accordance with JNC VII guidelines.

Study of Prescribing Pattern of Antihypertensive Drugs and Evaluation of the Prescription with JNC 8 Guidelines in North Karnataka Hospital

“…Where as study conducted by Anand R. Kalamdani et al showed that out of 100 patients, co morbidity was found in 64 subjects, the most common one being Diabetes mellitus (75%), followed by COPD (14%) and others. 6 According to JNC-8 guidelines 7-12 our study reveals that in patients without diabetes or CKD (greater than 60 years) 75.60% achieved the goal (less than 150/90mmHg) and patients without diabetes or CKD (less than 60 years) 64.30% achieved the goal (less than 140/90mmHg). Patients with Diabetes and without CKD (all ages) 50% achieved the goal (less than 140/90 mmHg) and patients with CKD with or without DM (all ages and races) 60% achieved the goal (less than 140/90 mmHg), which shows that the hypertensive goals were being achieved in this study.…”

Prescribing Pattern of Anti-Hypertensive Drugs and Adherence to JNC VII Guideline

“…Cost analysis showed that 57% of patients were charged below 500 rupees per month for their treatment. About 33% of total patients were charged between 501 and 1000 rupees per month, and 5% of patients were charged from 1001 to 1500 and more than 1500 rupees per month [14].…”