A prospective study of fever in the intensive care unit

Cîrciumaru, Bogdan; Baldock, G.; Cohen, Jonathan

doi:10.1007/s001340050928

Cited by 193 publications

(134 citation statements)

References 16 publications

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“…Th ese studies use a variety of defi nitions of fever and a range of methods to record temperature, making comparisons between studies diffi cult. In these studies, the presence of fever was associated with either an increased risk of death [30], [39]- [41] or no diff erence in mortality risk compared to a normal temperature [34]. Only two studies have evaluated the mortality risk of patients with sepsis separately from patients without sepsis [33], [35].…”

Section: Fever In Icu Patients With Infections Observational Studies mentioning

confidence: 99%

Fever Management in Intensive Care Patients with Infections

Young

Saxena

2014

Annual Update in Intensive Care and Emergency Medicine 2014

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Section: Fever In Icu Patients With Infections Observational Studies mentioning

confidence: 99%

Fever Management in Intensive Care Patients with Infections

Young

Saxena

2014

Annual Update in Intensive Care and Emergency Medicine 2014

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“…Circiumaru et al 1 followed 100 patients admitted to the ICU in a tertiary care, inner city hospital. Fever was present in 70% of patients admitted to the ICU, was apparent early in the ICU course, and correlated with scores on the Acute Physiology and Chronic Health Evaluation (APACHE) II but not with mortality.…”

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confidence: 99%

Fever in Trauma Patients: Evaluation of Risk Factors, Including Traumatic Brain Injury

Bengualid

Talari

Rubin

et al. 2015

American Journal of Critical Care

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Background The role of fever in trauma patients remains unclear. Fever occurs as a response to release of cytokines and prostaglandins by white blood cells. Many factors, including trauma, can trigger release of these factors. Objectives To determine whether (1) fever in the first 48 hours is related to a favorable outcome in trauma patients and (2) fever is more common in patients with head trauma. Method Retrospective study of trauma patients admitted to the intensive care unit for at least 2 days. Data were analyzed by using multivariate analysis. Results Of 162 patients studied, 40% had fever during the first 48 hours. Febrile patients had higher mortality rates than did afebrile patients. When adjusted for severity of injuries, fever did not correlate with mortality. Neither the incidence of fever in the first 48 hours after admission to the intensive care unit nor the number of days febrile in the unit differed between patients with and patients without head trauma (traumatic brain injury). About 70% of febrile patients did not have a source found for their fever. Febrile patients without an identified source of infection had lower peak white blood cell counts, lower maximum body temperature, and higher minimum platelet counts than did febrile patients who had an infectious source identified. The most common infection was pneumonia. Conclusions No relationship was found between the presence of fever during the first 48 hours and mortality. Patients with traumatic brain injury did not have a higher incidence of fever than did patients without traumatic brain injury. About 30% of febrile patients had an identifiable source of infection. Further studies are needed to understand the origin and role of fever in trauma patients. (American Journal of Critical Care. 2015; 24:e1–e5)

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“…Fever is common among the critically ill, occurring in at least half of patients admitted to the intensive care unit (ICU) (1,2). Among patients with acute lung injury (ALI), fever (defined as temperature .…”

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Fever Is Associated with Delayed Ventilator Liberation in Acute Lung Injury

et al. 2013

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Background: Acute lung injury (ALI) is characterized by inflammation, leukocyte activation, neutrophil recruitment, endothelial dysfunction, and epithelial injury, which are all affected by fever. Fever is common in the intensive care unit, but the relationship between fever and outcomes in ALI has not yet been studied. We evaluated the association of temperature dysregulation with time to ventilator liberation, ventilator-free days, and in-hospital mortality.

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A prospective study of fever in the intensive care unit

Abstract: Fever is a common event on the intensive care unit. It usually occurs early in the course, is frequently non-infective and is often benign. Prolonged fever is associated with a poor outcome. Post-operative fever is a well-recognised but poorly defined syndrome which requires further study.

Cited by 193 publications

References 16 publications

Fever Management in Intensive Care Patients with Infections

Fever Management in Intensive Care Patients with Infections

Fever in Trauma Patients: Evaluation of Risk Factors, Including Traumatic Brain Injury

Fever Is Associated with Delayed Ventilator Liberation in Acute Lung Injury

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