A Prospective Study of Clinicoradiologic-Urodynamic Correlation in Patients with Tuberculosis of the Spine

Singh, Roop; Tanwar, Milind; Singh, Santosh Kumar; Rohilla, Rajesh

doi:10.4103/ortho.ijortho_692_17

Cited by 2 publications

(5 citation statements)

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“…Анализ немногочисленных публикаций указывает на разнообразие вариантов уродинамических нарушений при инфекционных спондилитах, включая детрузорную гиперактивность, детрузорно-сфинк-терную диссинергию, нарушение сократительной способности детрузора, снижение комплаенса и др. [6][7][8]. При сравнении клинических, лучевых и уродинамических показателей у больных туберкулезным спондилитом с НДНМП (n = 16) и без нее (n = 14) Singh et al [7] указывают на развитие НДНМП при вовлечении в патологический процесс нервных корешков и задних отделов спинного мозга, при этом такие пациенты имели худшие результаты функционального восстановления через 6 и 12 мес.…”

Section: Discussionunclassified

“…[6][7][8]. При сравнении клинических, лучевых и уродинамических показателей у больных туберкулезным спондилитом с НДНМП (n = 16) и без нее (n = 14) Singh et al [7] указывают на развитие НДНМП при вовлечении в патологический процесс нервных корешков и задних отделов спинного мозга, при этом такие пациенты имели худшие результаты функционального восстановления через 6 и 12 мес. лечения.…”

Section: Discussionunclassified

“…Критерием нейрогенной дисфункции нижних мочевыводящих путей (НДНМП) является нарушение функции мочевого пузыря, уретры вследствие подтвержденного неврологического заболевания [4]. Оценить глобальную распространенность НДНМП при инфекционных спондилитах не представляется возможным в связи с малым количеством посвященных этому исследований: в большинстве работ такие состояния лишь подразумеваются в собирательном понятии «нарушение функции тазовых органов» [5][6][7][8]. Вместе с тем частота НДНМП у больных с верифицированным туберкулезным спондилитом достигает 50 % [6].…”

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“…Лишь небольшое число исследований с малой выборкой посвящено поиску взаимосвязи между характером МР-изменений и НДНМП у пациентов со спондилитами туберкулезной этиологии и ни одного при неспецифическом инфекционном поражении позвоночника [6][7][8].…”

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Neurogenic dysfunction of the lower urinary tract in infectious and inflammatory diseases of the spine: is there a correlation with clinical and radiological variants of myelopathy? Preliminary result of the analysis of a single-center cohort

Gorbunov,

Mushkin,

Kaumova

et al. 2023

Hir. pozvonoč.

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Objective. To study the relationship between clinical and radiation variants of myelopathy and types of the neurogenic dysfunction of the lower urinary tract in patients with infectious spondylitis.Material and Methods. A single-center cohort observational study was conducted with the analysis of medical records and a prospective examination of 20 patients with infectious spondylitis complicated by neurogenic dysfunction of the lower urinary tract.Results. Infectious spondylitis can be complicated by the development of various urodynamic disorders, including neurogenic detrusor hyperactivity (30 %), its combination with detrusor-sphincter dissinergia (30 %) and a decrease in detrusor contractility (40 %). In 50 % of patients, an urodynamic examination revealed an increase in detrusor pressure of more than 40 cm water. There was no connection between the development of any type of lower urinary tract dysfunction and MRI types of myelopathy according to Vendatam, as well as between the level of spinal cord compression and the severity of neurological disorders according to AIS.Conclusion. The results of the study do not confirm the existence of a relationship between the various characteristics of myelopathy in infectious spondylitis and the results of urodynamic examination. The limitation of the reliability of the results is the small number of observations. Studies with a larger sample are required to assess the relationship between the clinical and radiation characteristics of myelopathy and variants of neurogenic dysfunction of the lower urinary tract in patients with infectious spondylitis.

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Section: Discussionunclassified

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Neurogenic dysfunction of the lower urinary tract in infectious and inflammatory diseases of the spine: is there a correlation with clinical and radiological variants of myelopathy? Preliminary result of the analysis of a single-center cohort

Gorbunov,

Mushkin,

Kaumova

et al. 2023

Hir. pozvonoč.

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“…It depends on the age of the patient, stage of the disease, socioeconomics of the patient, proper compliance with the treatment, and neurological deficits. 17,18 Patients usually present with severe neurological deficits. Patients presenting at a younger age had a good neurological outcome as compared to patients with old age because of the micro-vascular changes in the spinal cord blood supply.…”

Section: Introductionmentioning

confidence: 99%

Postoperative Neurological Outcome in Spinal Tuberculosis Patients Presenting with Severe Neurological Deficits

Waqas Noor Chughtai,

Muhammad Adeel Razzaque,

Muhammad Shafiq

et al. 2023

Pak J Neurol Surg

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Objective: To determine the postoperative neurological outcome in spinal tuberculosis patients presenting with severe neurological deficits. Materials and Methods: 57 patients of 22 to 65 years of spinal tuberculosis were included in this study from January 2018 to March 2023. Data was collected from the hospital records of the patients who were admitted and operated on for tuberculosis of the spine. All regions of the spine were taken for study. ASIA scoring was done and patients were labeled from ASIA scores A to E. All patients were operated and postoperative ASIA scoring was also done on follow-up visits. An Independent sample t-test was used to assess the difference in the mean of these variables. Results: The mean age was 44.45 ± 8.54 years. Males were 39 and females 18. Preoperatively 27 patients had ASIA B, 28 patients had ASIA C and 02 patients had ASIA D score. All these patients improved postoperatively. The mean preoperative ASIA Score was 2.03 ± 2.4 and the mean postoperative ASIA score was 4.1 ± 1.3 withp-value of 0.02. Patients having old age, who present late and with poor grades in neurology had worse outcomes postoperatively. Conclusion: Patients with spinal tuberculosis presenting even with severe neurological deficits had significant improvement in neurology postoperatively. Keywords: Spinal tuberculosis (TB), American Spinal Injury Impairment Score (ASIA), Mycobacterium Tuberculosis, Potts disease, Trans-pedicular decompression and fusion, Laminectomy, Magnetic resonance imaging (MRI).

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A Prospective Study of Clinicoradiologic-Urodynamic Correlation in Patients with Tuberculosis of the Spine

Cited by 2 publications

References 12 publications

Neurogenic dysfunction of the lower urinary tract in infectious and inflammatory diseases of the spine: is there a correlation with clinical and radiological variants of myelopathy? Preliminary result of the analysis of a single-center cohort

Neurogenic dysfunction of the lower urinary tract in infectious and inflammatory diseases of the spine: is there a correlation with clinical and radiological variants of myelopathy? Preliminary result of the analysis of a single-center cohort

Postoperative Neurological Outcome in Spinal Tuberculosis Patients Presenting with Severe Neurological Deficits

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