A Prospective, Randomized Trial Comparing Laparoscopic Versus Conventional Techniques in Colorectal Cancer Surgery: A Preliminary Report

Milsom, Jeffrey W.; Böhm, Bartholomäus; Hammerhofer, Katherine A.; Fazio, Victor W.; Steiger, Ezra; Elson, Paul

doi:10.1016/s1072-7515(98)00132-x

Cited by 643 publications

(461 citation statements)

References 28 publications

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“…It was assumed that earlier outcomes could have been related to the neglect of tumor-free principles during the operations. RCT research includes that of Milson, Schwandner, CLASICC [9,10,17] and others, who reached the conclusion of the similar long-term benefits of laparoscopic and open resection for rectal cancer. Leung also concluded that there were similar long-term effects of laparoscopic and conventional surgery for recto sigmoid colon cancer [16] .…”

Section: Introductionmentioning

confidence: 99%

Clinical comparison of laparoscopyvsopen surgery in a radical operation for rectal cancer: A retrospective case-control study

Huang

Shen

Zhang

et al. 2015

WJG

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AIM:To assess the diverse immediate and longterm clinical outcomes, a retrospective comparison between laparoscopic and conventional operation was performed. METHODS:A total number of 916 clinical cases, from January 2006 to December 2013 in our hospital, were analyzed which covered 492 patients underwent the laparoscopy in radical resection (LRR) and 424 cases in open radical resection (ORR). A retrospective analysis was proceeded by comparing the general information, surgery performance, pathologic data, postoperative recovery and complications as well as long-term survival to investigate the diversity of immediate and long-term clinical outcomes of laparoscopic radical operation. Retrospective Study ORIGINAL ARTICLERESULTS: There were no statistically significance differences between gender, age, height, weight, body mass index (BMI), tumor loci, tumor node metastasis stages, cell differentiation degree or American Society of Anesthesiologists scores of the patients (P > 0.05). In contrast to the ORR group, the LRR group experienced less operating time (P < 0.001), a lower blood loss (P < 0.001), and had a 2.44% probability of conversion to open surgery. Postoperative bowel function recovered more quickly, analgesic usage and the average hospital stay (P < 0.001) were reduced after LRR. Lymph node dissection during LRR appeared to be slightly more than in ORR (P = 0.338). There were no obvious differences in the lengths and margins (P = 0.182). And the occurrence rate in the two groups was similar (P = 0.081). Overall survival rate of ORR and LRR for 1, 3 and 5 years were 94.0% and 93.6% (P = 0.534), 78.1% and 80.9% (P = 0.284) and 75.2% and 77.0% (P = 0.416), respectively. CONCLUSION:Laparoscopy as a radical operation for rectal cancer was safe, produced better immediate outcomes. Long-term survival of laparoscopy revealed that it was similar to the open operation.

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Section: Introductionmentioning

confidence: 99%

Clinical comparison of laparoscopyvsopen surgery in a radical operation for rectal cancer: A retrospective case-control study

Huang

Shen

Zhang

et al. 2015

WJG

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“…The first successful laparoscopic sigmoidectomy for cancer was reported in 1991 by Jacob's et al [1]. However, the laparoscopic technique was not adopted by surgeons worldwide because of concerns about the adequacy of intra-abdominal exploration and the initial reports of high incidence of port-site metastases [2,3]. As a consequence, laparoscopic surgery for colon cancer was not adopted widely until initial reports of few randomized trials were published in [2002][2003][2004][2005] period [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic Colonic Resection for Rectosigmoid Colonic Tumours: A Retrospective Analysis and Comparison with Open Resection

et al. 2010

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Laparoscopic approach for treatment of colorectal malignancy is gaining acceptance gradually; however the benefits of laparoscopic surgery in colonic and rectal tumours is still open to debate. This study aims at a retrospective analysis of operative and short term outcome of patients with rectosigmoid tumours. A retrospective analysis of operative, postoperative and short-term outcome of 62 patients who underwent laparoscopic colorectal resection for cancer of rectosigmoid region were compared with a same number of parameters-matched patients who underwent open colorectal resection. Blood transfusion requirement was significantly more in the open group compared to the laparoscopy group (38.7% versus 6.4%, p=0.001). ICU stay was less in the laparoscopy group (p=<0.05) and they were started on oral liquid diet earlier (p=0.013). The number of the lymph nodes retrieved, positive distal margin and radial involvement were similar in both groups. The hospital stay was significantly shorter in laparoscopy group (8.4 versus 13.8 days, p < 0.05). Radical operation for rectosigmoid tumors is technically feasible with laparoscopic surgery. Laparoscopic approach is associated with less blood loss, transfusion and significantly less ICU stay. Laparoscopic group recovers early and needs less hospital stay

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“…Adequate margin of resection, nodal dissection, and anastomotic creation have been reported [3,5]. Besides technical considerations, the extent of patient-related benefits is unclear.…”

mentioning

confidence: 99%

The impact of laparoscopy on cancer management

Greene

2000

Surg Endosc

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A Prospective, Randomized Trial Comparing Laparoscopic Versus Conventional Techniques in Colorectal Cancer Surgery: A Preliminary Report

Cited by 643 publications

References 28 publications

Clinical comparison of laparoscopyvsopen surgery in a radical operation for rectal cancer: A retrospective case-control study

Clinical comparison of laparoscopyvsopen surgery in a radical operation for rectal cancer: A retrospective case-control study

Laparoscopic Colonic Resection for Rectosigmoid Colonic Tumours: A Retrospective Analysis and Comparison with Open Resection

The impact of laparoscopy on cancer management

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