A Prospective Randomized Study to Compare the Effectiveness of Honey Dressing vs. Povidone Iodine Dressing in Chronic Wound Healing

Gulati, Sonia; Qureshi, Ashia; Srivastava, Anurag; Kataria, Kamal; Kumar, Prabin; Ji, Acharya Balakrishna

doi:10.1007/s12262-012-0682-6

Cited by 37 publications

(27 citation statements)

References 15 publications

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“…edema, hotness, and redness) within 10 days in all patients, which was attributed to the anti-edema and antimicrobial effects of Egyptian honey. Similar findings were observed when several honey samples were tested on more than 787 patients from the nine following countries: Malaysia (Shukrimi et al, 2008), China (Guo & Fu, 2013), Pakistan (Jan et al, 2012), Greece (Kamaratos et al, 2014), Iran (Siavash et al, 2015), Saudi Arabia (Imran et al, 2015), India (Gulati et al, 2014), Yemen (Mohamed et al, 2014) and Russia (Mohamed et al, 2015).…”

Section: Effect Of Honey On Febrile Neutropeniasupporting

confidence: 57%

Chemical Composition, Nutritional Functions, and Antioxidant Activities of Honeys in Africa

Tahir

Mariod

Mahunu

et al. 2019

Journal of Apicultural Science

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Honey production in Africa is considered an integral part of folk medicine and provides an opportunity for poor rural communities to increase their economic sustainability. In this review, we provide and discuss the data available on the positive nutritional value and health properties of honey harvested from Africa. Besides sugar, honey contains protein and amino acids, with proline which is about 50% of the total amino acids, vitamins, enzymes, some minerals (Na, K, Mg, Ca, Zn, Cu, Mn, Fe, P, S), trace elements (Mn, Ni, Li, F, I, Cl, Sr, Co) and polyphenol compounds. The paper reviewed studies on the use of African honey with anti-inflammatory, antioxidant, antibacterial, antifungal, anti-breast cancer, antidiabetic and antimycotic properties and also its positive effects on infertility (asthenozoospermia), febrile neutropenia and diabetic foot ulcers.

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Section: Effect Of Honey On Febrile Neutropeniasupporting

confidence: 57%

Chemical Composition, Nutritional Functions, and Antioxidant Activities of Honeys in Africa

Tahir

Mariod

Mahunu

et al. 2019

Journal of Apicultural Science

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“…Research has confirmed that curcumin aids wound healing by stimulating the migration of macrophages, neutrophils and fibroblasts to the wound, accelerates the wound contraction, formation of granulation tissue, neovascularization and reepithelialisation ( Results represented that width of sutured line markedly decreased from day 7 ( Table 1) in all wounds irrespective of treatment. It may supports Gulati et al (2014), where it is indicated that contraction of wound is maximal 5-15 days after injury which is defined as the centripetal movement of wound edges that facilitates closure of a wound defect.…”

Section: Resultsmentioning

confidence: 99%

Wound healing by marigold (Calendula officinalis) and turmeric (Curcuma longa) Paste: A comparative approach

Paul

Rahman²,

Mahmud

et al. 2017

J Adv Vet Anim Res

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Objective: This experiment was conducted to evaluate the therapeutic potency of marigold flower (Calendula officinalis) and turmeric (Curcuma longa) rhizome paste in wound healing. Materials and methods: Thirty six aseptic surgical wounds were tooled in six non-pregnant black Bengal goats dividing them in 3 groups. Month long information and follow-up examinations along with complications such as edema, wound dehiscence, suture abscess, exudation etc. were studied. Wound healing was assessed by observing some morphological characters as well as histopathological changes of the wounded area. Results: Results revealed that negligible elevation of suture line (1.17±0.11 mm) and significant (P<0.01) reduction of sutured area were observed in goats of turmeric group at day 3 (D3) and 7 (D7) respectively. Moreover, histologic appearance of wound of the similar group displayed splendid development of keratin layer and collagen fiber than the others from day 3 (D3). However, therapeutic efficacy of marigold flower paste was not up to the mark as turmeric in this experiment. Control group treated with povidone iodine, showed good results but took long time. Conclusion: This study could patronize veterinarians to consider the use of herbal plants specially turmeric as a great wound healer. It will also reduce toxicities created by haphazard use and applications of pharmaceutical products. The findings of this very experiment will not only prevent the skin degradation but also help to maintain the good health status of animals. KEYWORDS CORRESPONDENCE:# Sattwikesh Paul, Department of Surgery & Radiology, FVMAS, BSMRAU, Gazipur-1706. Bangladesh. E-mail: paulsattwik@gmail.com

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“…However, in some cases the control group had a better outcome [172], probably promoted by C-I [165], although PVP-I showed worse results than OCT and PHMB in terms of biocompatibility [173]. On the one hand, PVP-I has been shown to be less comfortable than medical honey and less effective in reducing the wound size than silver dressings [174], but on the other hand, it was superior to silver and C-I dressings regarding the amount of pain during medical dressing changes [175]. …”

Section: Iodophorementioning

confidence: 99%

Consensus on Wound Antisepsis: Update 2018

Krämer

Dissemond²,

Kim³

et al. 2017

Skin Pharmacol Physiol

243

215

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Wound antisepsis has undergone a renaissance due to the introduction of highly effective wound-compatible antimicrobial agents and the spread of multidrug-resistant organisms (MDROs). However, a strict indication must be set for the application of these agents. An infected or critically colonized wound must be treated antiseptically. In addition, systemic antibiotic therapy is required in case the infection spreads. If applied preventively, the Wounds-at-Risk Score allows an assessment of the risk for infection and thus appropriateness of the indication. The content of this updated consensus recommendation still largely consists of discussing properties of octenidine dihydrochloride (OCT), polihexanide, and iodophores. The evaluations of hypochlorite, taurolidine, and silver ions have been updated. For critically colonized and infected chronic wounds as well as for burns, polihexanide is classified as the active agent of choice. The combination 0.1% OCT/phenoxyethanol (PE) solution is suitable for acute, contaminated, and traumatic wounds, including MRSA-colonized wounds due to its deep action. For chronic wounds, preparations with 0.05% OCT are preferable. For bite, stab/puncture, and gunshot wounds, polyvinylpyrrolidone (PVP)-iodine is the first choice, while polihexanide and hypochlorite are superior to PVP-iodine for the treatment of contaminated acute and chronic wounds. For the decolonization of wounds colonized or infected with MDROs, the combination of OCT/PE is preferred. For peritoneal rinsing or rinsing of other cavities with a lack of drainage potential as well as the risk of central nervous system exposure, hypochlorite is the superior active agent. Silver-sulfadiazine is classified as dispensable, while dyes, organic mercury compounds, and hydrogen peroxide alone are classified as obsolete. As promising prospects, acetic acid, the combination of negative pressure wound therapy with the instillation of antiseptics (NPWTi), and cold atmospheric plasma are also subjects of this assessment.

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A Prospective Randomized Study to Compare the Effectiveness of Honey Dressing vs. Povidone Iodine Dressing in Chronic Wound Healing

Abstract: To compare the healing of chronic wounds with honey dressing vs. Povidone iodine dressing in adult subjects with chronic wounds of ≥6 weeks of duration, attending wound care clinic in Surgical Out Patient

Cited by 37 publications

References 15 publications

Chemical Composition, Nutritional Functions, and Antioxidant Activities of Honeys in Africa

Chemical Composition, Nutritional Functions, and Antioxidant Activities of Honeys in Africa

Wound healing by marigold (Calendula officinalis) and turmeric (Curcuma longa) Paste: A comparative approach

Consensus on Wound Antisepsis: Update 2018

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