Abstract:Background: Procedure tract metastasis (PTM) may complicate pleural procedures in malignant pleural mesothelioma (MPM) patients and cause significant morbidity. Aim: To evaluate the effectiveness of prophylactic radiotherapy (RTH) in preventing PTM and reducing pain. Methods: Forty patients with MPM, who had a pleural invasive procedure within the preceding 15 days, were randomized in a 1:1 ratio to receive prophylactic RTH to the procedure site (21 Gy in three consecutive daily fractions using 9MeV) vs. no RT… Show more
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