A Prospective Randomized Study Comparing Non-absorbable Polypropylene (Prolene®) and Delayed Absorbable Polyglactin 910 (Vicryl®) Suture Material in Mass Closure of Vertical Laparotomy Wounds

Abstract

Wound dehiscence is a postoperative complication encountered following abdominal surgery. A prospective randomized study was conducted to compare the incidence of wound dehiscence with a delayed absorbable and a nonabsorbable suture material in the mass closure of vertical laparotomy wounds. In one group, 100 patients were analyzed after closure with Prolene®, and in another group, 100 patients were analyzed after closure with Vicryl®. The incision was closed by continuous far and near suture technique using polypropylene (Prolene) suture in one group and a synthetic delayed absorbable polyglactin 910 (Vicryl) suture in the other group. There was significant difference in the incidence of wound dehiscence between the two groups: 6 % with Prolene and 17 % with Vicryl, (χ 2 05.944, 1 DF, P value00.0148). The overall incidence of wound dehiscence was 11.5 % in this study. The incidence of wound dehiscence in both the study groups was higher than expected as compared to previous literature. There was a significant difference between the two suture materials. In our study, Prolene is a better suture material for closure of vertical laparotomy wounds.

Clinical Study on Factors Influencing Wound Dehiscence in Emergency Exploratory Laparotomy

“…In study by Pandey S et al, overall incidence of wound dehiscence was 11.5% and 17% in patients in whom mass closure was done with Vicryl. 8 In current study 12.6% of patients developed wound dehiscence which co-relates with many of Asian studies. Moreover, the higher incidence may be because the study included only emergency cases.…”

Interrupted Braided Sutures versus Running Monofilament Sutures in the Prevention of Abdominal Wound Dehiscence : A Prospective Nonrandomized Case-Control Trial

“…), sound surgical wound closure remains the only potentially modifiable factor to prevent wound dehiscence .Many methods have been advocated to prevent AWD including the use of different type of suture material, different techniques of suturing including tension sutures, use of relaxing incisions and even use of absorbable mesh. (13)(14)(15)(16)(17)(18) The hypothesis of our study was partly based on the intraoperative findings at the time of revision of dehisced wounds. A common finding was sutures cutting through the fascia leading to loosening of the whole repair in cases of continuous wound closure.…”

Suture choice to reduce occurrence of surgical site infection, hernia, wound dehiscence and sinus/fistula: a network meta-analysis

“…Thirty-one studies (summarised in Table 1) were identified that were appropriate in their question and SURGERY IN GENERAL Table 1 Author quality. These included studies investigating polyglactin, 1,4,[6][7][8][9][10][11][12][13][14] polydioxanone (PDS), 5,[15][16][17][18][19][20][21][22][23][24][25][26][27] polypropylene, 28,29 nylon, [30][31][32] polyglycolic acid (PGA), 33 polyglyconate, triclosan-coated polyglactin, triclosan-coated polydioxanone, Ethibond®, steel, poly(L-lactide-co-glycolide) (PLG) and Polysorb®.…”