A prospective, randomized, controlled trial of covered expandable metal stents in the palliation of malignant esophageal obstruction at the gastroesophageal junction

Abstract

Membrane-covered stents have significantly better palliation than conventional bare metal stents because of decreased rates of tumor ingrowth that necessitate endoscopic reintervention for dysphagia.

Self-expandable metallic stent placement for malignant obstruction in patients with locally recurrent gastric cancer

“…This result is in agreement with the results of studies of primary malignant GOO in which the mean dysphagia score improved considerably by day 7, and the improvement was maintained up to day 30 [13,18]. When considering improved quality of life and performance score after stent placement [19,20], it might allow the chance for additional chemotherapy.…”

“…The early complication rate of 5% in our study is comparable to those in previous reports. All of the late complications occurred more than 1 month after stent insertion, and these were migration or restenosis due to tumor overgrowth or ingrowth, comparable to the results of previous studies [13,17,24].…”

“…Although stent insertion is considered more difficult in recurrent rather than primary malignant GOO, because of altered anatomy, the overall technical success of stent insertion was 92%, and clinical success was 90% in our study. These figures are comparable to those achieved with inoperable esophagogastric junction or cardia gastric cancer (95-100%) [13,14], or with malignant gastroduodenal obstruction (87-97%) [15]. Our results suggest that endoscopic SEMS insertion is effective even with obstruction due to recurrent gastric cancer.…”

Self-expandable metal stents are a valid option in long-term survivors of advanced esophageal cancer

“…SEMS improve quality of life (5) by allowing the relief of dysphagia (6) and optimizing the nutritional/functional status for subsequent surgery or chemo/radiotherapy. However, they are associated with a risk of adverse events (AEs) such as hemorrhage, pain, fistula and perforation (7,8).…”

Plastic tube-assisted gastroscopic removal of embedded esophageal metal stents: A case report

“…The use of fully covered self-expandable esophageal metal stents has favorable results in treating a variety of benign and malignant esophageal strictures and esophageal fistulae [1][2][3][4][5][6] . However, stent placement over a prolonged period can result in hyperplastic tissue overgrowth on both ends of the stent, leading to in-stent restenosis [7][8][9] .…”