A Prospective Open-Label Study for Treatment of Infraorbital Hollows Using a Volumizing Hyaluronic Acid Filler

Abstract

IMPORTANCE: Hyaluronic acid (HA) filler can be used for the successful correction of infraorbital hollowing with high patient satisfaction. OBJECTIVE: Prospectively report efficacy, patient satisfaction, and early adverse events following HA filler treatment of infraorbital hollows using objective metrics and validated patient reported outcomes. DESIGN: Twenty-one (n=21) participants underwent injection of VYC-20L (JUVÉDERM® VOLUMA™ XC; Allergan Aesthetics, Irvine, CA ) for treatment of infraorbital hollowing. Early adverse events surveys were completed at as well as FACE-Q satisfaction surveys before and 1-month after treatment. Pre- and post-treatment photos were graded using the Allergan Infraorbital Hollows Scale. MAIN OUTCOMES: Difference in infraorbital hollowing using Allergan Infraorbital Hollows Scale, satisfaction with eyes, decision to treat, and early adverse events measured using FACE-Q surveys. RESULTS: Infraorbital hollow graded improvement with VYC-20L was significant (p<.001). FACE-Q Satisfaction with Eyes scores on average were 27 points higher after treatment (p<.001). The mean FACE-Q Satisfaction with Decision score was 74.1%. The most common short-term adverse symptoms were tenderness (67%), swelling (62%), bruising (52%). CONCLUSIONS: VYC-20L has a high patient satisfaction profile with infraorbital hollow improvement and decision to treat. Satisfaction scores were consistent with our previous retrospective study.