A prospective observational study to assess quality of life and prescription pattern in osteoarthritis patients at tertiary health centre in Mumbai

Jadhav, Manoj P.; Jadhav, Priyanka; Mutke, Amol P; Sonawane, Supriya D; Patil, Bhushan D.; Naik, Narendra B; Sonawale, Archana

doi:10.4103/0019-5359.103963

Cited by 7 publications

(7 citation statements)

References 6 publications

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“…8 The mean age of osteoarthritis affected population in our study was 56.46+/-7.4 years. The same age group is also commonly affected by osteoarthritis according to a study done by Kulkerni et al 9 Among various sites involved in osteoarthritis, knee joint (87.33%) was most commonly affected site which is in accordance with other such studies including Jadhav et al 7 and Ullal et al 6 Average number of drugs per prescription is an integral determinant prescription audit. 10 In our study, the average number of drugs prescribed per prescription was 2.62+/-0.46.…”

Section: Discussionsupporting

confidence: 71%

“…This is in accordance with a study done by Ullal et al and Jadhav et al, in which 57.14% and 70.56% of affected patients were females respectively. 6,7 The importance of estrogen in prevention of osteoarthritis is explained in the study by Rowen et al with regards to the age distribution, a total of 176 patients (58.67%) belonged to the age group of 46-60years. 8 The mean age of osteoarthritis affected population in our study was 56.46+/-7.4 years.…”

Section: Discussionmentioning

confidence: 99%

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A prospective observational study of prescription pattern of drugs used in the treatment of osteoarthritis in a tertiary care hospital

Patil

Nara

2016

Int J Basic Clin Pharmacol

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Background: Treatment of Osteoarthritis aims at reducing pain and improving mobility. NSAIDS are commonly prescribed for symptomatic relief despite well documented adverse effects. Paracetamol with its better safety profile is recommended as the initial analgesic of choice. Osteoarthritis has significant socio-economic impact on the patients and not many studies are available to reflect upon the prescription pattern of drugs in Osteoarthritis. Hence, this study was chosen to generate important feedback to the clinician. The objectives of the study were to study the prescribing pattern of drugs used in the treatment of Osteoarthritis in Tertiary care hospital.Methods: Prescription for 300 osteoarthritis patients collected cross-sectional for 6 months from orthopedic out-patient department were analyzed.Results: 60% of females were affected. Average age of study was 56.46+/- 7.4 years. Knee joint (87.33%) was most commonly affected joint. Average number of drugs prescribed was 2.62 +/- 0.76. Out of 786 drugs prescribed 45.8% were NSAIDs. Paracetamol was underutilized.Conclusions: Paracetamol was underutilized while other NSAIDs were over prescribed.

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Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 99%

A prospective observational study of prescription pattern of drugs used in the treatment of osteoarthritis in a tertiary care hospital

Patil

Nara

2016

Int J Basic Clin Pharmacol

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“…In this present study, demographic distribution projected that OA was much more prevalent in females (60%) as compared to males (40%). Our study coincides with a study conducted by Ullal and Narendranath [8] and Jadhav et al [9] in which they documented 57.14% and 70.56% of patients diagnosed with OA were female patients [6,7]. Further a prospective and observational study conducted by Kulkarni et al among 84 patients also concluded that OA was more prevalent in females (63.1 %), and these results are parallel to our study in which 60% of females were duly affected by OA [10].…”

Section: Discussionsupporting

confidence: 93%

An an Observational Study of Prescription Pattern of Drugs for Osteoarthritis in a North Indian Medical College

Ummat¹,

Singh²,

Kochhar³

2019

Asian J Pharm Clin Res

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Objective: The objective of the study is to analyze the prescription pattern of drugs for osteoarthritis (OA) in a north Indian medical college collaborated with a tertiary care hospital. Methods: An observational study was conducted on 300 patients diagnosed with OA in the department of orthopedics in collaboration with the department of pharmacology, and thus, prescription was collected as in a cross-sectional manner for 6 months and the same were analyzed in the Department of Orthopedics in tertiary care hospital collaborated with medical college. Results: The average age of patients participating in this present study was 56.46±7.4 years with affected age group of 46-60 years. 60 % of females were affected by osteoarthritis outnumbering male (40 %) patients in this present study. The most commonly involved joint was knee joint (87.33 %) in patients diagnosed with osteoarthritis followed by back (6.67 %) and hip joint (6%). The combination therapy (90 %) outweighed monotherapy (10 %) with preferred route of drug administration as oral route (90 %) followed by topical route (10 %). The average number of drugs prescribed for patients of osteoarthritis was 2.62±0.76. This present study concludes that NSAIDs (45.8%) were prescribed most commonly. However, the drug paracetamol was lesser prescribed and other drugs such as Diclofenac (27.22 %) and acetaminophen (34.44 %) most of all followed by Nimesulide (16.67 %), ibuprofen (13.33 %) and Rofecoxib/valdecoxib (8.33 %) were prescribed. Conclusion: This present study concludes that NSAIDs were most commonly prescribed as p-drugs while paracetamol was undermined prescribed.

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“…In the reviewed literature there is a significant correlation between the level of pain and 347 disability in OA patients. Pain created various limitations to varying degrees, not only in the 348 performance of professional duties, but also in daily activities and in the pursuing of personal 349 interests (Jadhav et al, 2001). Reis et al (2014) indicate that in women diagnosed with OA, 350 there is a significant relationship between the pain and the level of disability during performing 351 basic daily life activities, which is similar to our study result.…”

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confidence: 83%

Peer Review #2 of "Identification of demographic factors and health problems that affect the acceptance of disease and health behaviors of patients with osteoarthritis (v0.2)"

2017

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A prospective observational study to assess quality of life and prescription pattern in osteoarthritis patients at tertiary health centre in Mumbai

Abstract: Osteoarthritis has a significant impact on quality of life, only partly ameliorated by anti-arthritic drugs, as assessed by the WOMAC scale in this study population. Further, a study with larger sample size is needed to further support our findings.

Cited by 7 publications

References 6 publications

A prospective observational study of prescription pattern of drugs used in the treatment of osteoarthritis in a tertiary care hospital

A prospective observational study of prescription pattern of drugs used in the treatment of osteoarthritis in a tertiary care hospital

An an Observational Study of Prescription Pattern of Drugs for Osteoarthritis in a North Indian Medical College

Peer Review #2 of "Identification of demographic factors and health problems that affect the acceptance of disease and health behaviors of patients with osteoarthritis (v0.2)"

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