A prospective multi-country observational trial to compare the incidences of diabetic ketoacidosis in the month of Ramadan, the preceding month, and the following month (DKAR international)

Abdelgadir, Elamin; Hassanein, Mohamed; Bashier, Alaaeldin; Abdelaziz, Sulaf; Baki, S.; Chadli, A.; Askaoui, Sara; Nawal, El Ansari; Slim, I.; Ghizlane, El Mghari; Hafidh, Khadija; Alawadi, Fatheya

doi:10.1186/s40200-016-0272-4

Cited by 21 publications

(10 citation statements)

References 17 publications

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“…Another study revealed a substantial increment in cases of hypoglycemia during Ramadan as compared to other lunar months, particularly for insulin treated diabetics in comparison to those who use oral hypoglycemic agents (OHA). This is different from the heightened hospitalization rate and incidence caused by DKA in Ramadan with prolonged acidosis as obtained by Abdelgadir and colleagues [ 5 ]. This prospective study was conducted by major hospitals in United Arab Emirates, Sudan, Tunisia, and Morocco, involving 167 patients from lunar month before Ramadan (Shaban) until a month after fasting period (Shawal).…”

Section: Introductioncontrasting

confidence: 68%

The impact of Ramadan on visits related to diabetes emergencies at a tertiary care center

et al. 2021

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Background Ramadan is the ninth month of the Islamic calendar were Muslims fast from dawn until sunset. This prolonged fasting period might have an impact on patients with diabetes and their disease control. This study aimed to determine the variation in visits at the Emergency Room department (ER) during Ramadan in comparison with other lunar months at a tertiary care hospital in Jeddah city in relation to the diabetes emergencies. Methodology A retrospective cross-sectional study was conducted using electronic medical record review of patients with diabetes emergencies who visited ER of a Military hospital, from 9th to 11th lunar months during 2017–2018. Diabetes patients who visited ER and aged more than 18 years old were included. Frequency of ER visits, sociodemographic characteristics and clinical features were determined. Chi-square test, Student ‘s t-test and one-way ANOVA at p < 0.05 were used in assessing associations between variables. Results Within the selected study period, a total of 24,498 admissions were recorded in ER. The prevalence of diabetes emergencies visits was only 0.84%. Based on inclusion criteria, a total of 133 subjects were included in the study (54.1% men, 45.9% women). Majority of whom (73.7%) were on insulin therapy, and more than half of whom (51.9%) were type 2 diabetes. There was a significant difference (p = 0.001) in the prevalence of diabetes emergencies visits between the three lunar months Shaban, Ramadan and Shawal, 7, 5 and 4%, respectively. However, the highest prevalence was not in Ramadan. Despite some correlations were identified, the study found no significant differences between frequency of ER visits and various demographic, clinical factors and diabetes profile between Ramadan and other both preceding and succeeding lunar month. Conclusion In contrary with previous studies, a downward trend of prevalence, from Shaban to Ramadan, to Shawal was found. This indicated that fasting during month of Ramadan does not impact negatively on the diabetes emergencies in comparison with other months. Hyperglycemia among type 2 diabetes and insulin treated patients were recorded the highest feature of diabetes emergences visits during the three months studied with no significant differences between the months. These findings highlight the need of type 2 and insulin treated patients to be thoroughly assess by the Primary Care physicians and in-depth health education and guidance should be given to them.

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Section: Introductioncontrasting

confidence: 68%

The impact of Ramadan on visits related to diabetes emergencies at a tertiary care center

et al. 2021

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“…Singapore (17), France (18), United Kingdom (19)(20)(21)(22), Qatar (23), United Arab Emirates (24,25), Egypt (26), Lebanon (27) and Pakistan (28). Several multi-center studies were included in this review (29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41). Eight studies were randomized controlled trials (15,16,19,27,29,34,38,39) Five studies reported on hospital admissions during Ramadan (15,18,24,31,37), but were not included in the meta-analysis due to different methods of outcome reporting.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Several multi-center studies were included in this review (29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41). Eight studies were randomized controlled trials (15,16,19,27,29,34,38,39) Five studies reported on hospital admissions during Ramadan (15,18,24,31,37), but were not included in the meta-analysis due to different methods of outcome reporting. One study reported on the number of cases with DKA and medication adherence at two time points (37), but was not eligible as recommended by the Cochrane group, the meta-analysis should combine results from two or more separate studies (10).…”

Section: Study Characteristicsmentioning

confidence: 99%

Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis

Gad

Hayat

Almuhannadi

et al. 2021

Diabetes Research and Clinical Practice

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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“…7 However, fasting can increase the risk of hypoglycemia 6,8 and diabetic ketoacidosis. 9 Further, individuals who adjust their own medications are more likely to experience severe hypoglycemia during Ramadan. 6 By comparison, individualized education during Ramadan can help Muslims with type 2 diabetes lose weight, improve glycemic control and avoid severe hypoglycemia.…”

Section: Practicetoolmentioning

confidence: 99%

Managing medications during Ramadan fasting

Grindrod

Alsabbagh

2017

Can Pharm J

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Fasting during RamadanRamadan is a warm, community celebration for practising Muslims that involves a month of fasting, worship and feasting. Over the month of Ramadan, between dawn and sunset, individuals refrain from eating, drinking, smoking, intercourse and taking oral medications. For Muslims, the goal is to improve their spiritual and physical state and to fortify their relationship with God.Each day of Ramadan begins with a predawn meal known as Suhoor that includes enough food and water to sustain the individual over a long day of fasting. At sunset, families break the fast together during a celebratory evening meal known as Iftar, often eating with neighbours and extended family. Iftar is usually rich in calories and is taken with a large amount of fluids.Every year, Ramadan falls on the ninth month of the lunar Islamic calendar, which means it moves ahead by a couple of weeks on the Western (Gregorian) calendar. For the next few years, Ramadan will fall over the longest days of the year in May and June. For Muslims in Canada, this means that fasting can last up to 17 hours a day.

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A prospective multi-country observational trial to compare the incidences of diabetic ketoacidosis in the month of Ramadan, the preceding month, and the following month (DKAR international)

Cited by 21 publications

References 17 publications

The impact of Ramadan on visits related to diabetes emergencies at a tertiary care center

The impact of Ramadan on visits related to diabetes emergencies at a tertiary care center

Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis

Managing medications during Ramadan fasting

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