A Prospective Longitudinal Study of Mental Health Symptoms Among Perinatally HIV-Infected and HIV-Exposed but Uninfected Urban Youths

Mutumba, Massy; Bauermeister, José A.; Elkington, Katherine S.; Bucek, Amelia; Dolezal, Curtis; Leu, Cheng Shiun; Mellins, Claude A.

doi:10.1016/j.jadohealth.2015.12.014

Cited by 30 publications

(21 citation statements)

References 39 publications

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“…In total 40% of PHIV and 31% of HIV-affected participants scored mild to severe for anxiety and 16% and 17% mild to moderate for depression. These results are similar to other recent studies finding no evidence of a difference in prevalence of mental health problems by HIV status, (Elkington et al., 2011 ; Gadow et al., 2012 ; Mellins et al., 2012 ; Mutumba et al, 2016 ) and suggest that contextual factors rather than HIV itself may have an important role (Mellins & Malee, 2013 ). Another explanation for the lack of difference by HIV status is that anxiety and depression in young people with PHIV may be lessened through regular contact with health services and mental health support (Gadow et al., 2012 ).…”

Section: Discussionsupporting

confidence: 91%

“…Prevalence of mental health problems in young people with PHIV varies across different populations in the literature (Chernoff, Nachman, & Williams, 2009 ; Gadow et al., 2012 ; Malee et al., 2011 ; Mellins et al., 2009 ; Mutumba et al, 2016 ). This may be due to different mental health problems being assessed, with differing definitions, and different healthcare settings and contextual factors.…”

Section: Discussionmentioning

confidence: 99%

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Anxiety and depression symptoms in young people with perinatally acquired HIV and HIV affected young people in England

et al. 2018

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Adolescents with perinatal HIV (PHIV) may be at higher risk of anxiety and depression than HIV negative young people. We investigated prevalence of anxiety and depression symptoms in 283 PHIV and 96 HIV-affected (HIV-negative) young people in England recruited into the Adolescents and Adults Living with Perinatal HIV (AALPHI) cohort. We used Hospital Anxiety and Depression Scale (HADS) scores and linear regression investigated predictors of higher (worse) scores.115 (41%) and 29 (30%) PHIV and HIV-affected young people were male, median age was 16 [interquartile range 15,18] and 16 [14,18] years and 241 (85%) and 71 (74%) were black African, respectively. There were no differences in anxiety and depression scores between PHIV and HIV-affected participants. Predictors of higher anxiety scores were a higher number of carers in childhood, speaking a language other than English at home, lower self-esteem, ever thinking life was not worth living and lower social functioning. Predictors of higher depression scores were male sex, death of one/both parents, school exclusion, lower self-esteem and lower social functioning. In conclusion, HIV status was not associated with anxiety or depression scores, but findings highlight the need to identify and support young people at higher risk of anxiety and depression.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Anxiety and depression symptoms in young people with perinatally acquired HIV and HIV affected young people in England

et al. 2018

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“…Due to the complexity of the effects of HIV, appropriate comparison groups could include adolescents who were perinatally exposed to HIV, but remain HIV uninfected, as well as adolescents without any history of HIV exposure, but from similar communities and backgrounds. Available studies that compare perinatally infected, HIV-positive adolescents with those perinatally exposed to HIV, but uninfected largely suggest that there are not significant differences in the rates or types of psychiatric disorders between these groups in comparison with those with no HIV exposure [11,22,24,25]. …”

Section: Resultsmentioning

confidence: 99%

Mental health challenges among adolescents living with HIV

Vreeman

McCoy

Lee

2017

Journal of the International AIDS Society

239

234

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Introduction: Mental health is a critical and neglected global health challenge for adolescents infected with HIV. The prevalence of mental and behavioural health issues among HIV-infected adolescents may not be well understood or addressed as the world scales up HIV prevention and treatment for adolescents. The objective of this narrative review is to assess the current literature related to mental health challenges faced by adolescents living with HIV, including access to mental health services, the role of mental health challenges during transition from paediatric to adult care services and responsibilities, and the impact of mental health interventions.Methods: For each of the topics included in this review, individual searches were run using Medline and PubMed, accompanied by scans of bibliographies of relevant articles. The topics on which searches were conducted for HIV-infected adolescents include depression and anxiety, transition from paediatric to adult HIV care and its impact on adherence and mental health, HIV-related, mental health services and interventions, and the measurement of mental health problems. Articles were included if the focus was consistent with one of the identified topics, involved HIV-infected adolescents, and was published in English.Results and Discussion: Mental and behavioural health challenges are prevalent in HIV-infected adolescents, including in resource-limited settings where most of them live, and they impact all aspects of HIV prevention and treatment. Too little has been done to measure the impact of mental health challenges for adolescents living with HIV, to evaluate interventions to best sustain or improve the mental health of this population, or to create healthcare systems with personnel or resources to promote mental health.Conclusions: Mental health issues should be addressed proactively during adolescence for all HIV-infected youth. In addition, care systems need to pay greater attention to how mental health support is integrated into the care management for HIV, particularly throughout lifespan changes from childhood to adolescence to adulthood. The lack of research and support for mental health needs in resource-limited settings presents an enormous burden for which cost-effective solutions are urgently needed.

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“…Children who are infected with HIV/AIDS face life-long risk of related illnesses, and are more likely to experience cognitive and motor development delays, stigma, trauma, and low mood (Vreeman et al 2015, Abubakar et al, 2008; Sherr et al, 2009). Children who have lost one or both parents to HIV are at increased risk of mental health problems (Mutumba et al 2016, Stein et al 2014, Sherr et al 2014), such as internalising disorders and post-traumatic stress (Cluver & Gardner, 2007), and are often living in alternative care situations. HIV exhausts family financial resources, through job loss or reduced productivity due to illness, the expenses associated with accessing health care, and the high cost of funerals (Thomas, 2006).…”

Section: Introductionmentioning

confidence: 99%

Interventions to improve psychosocial well-being for children affected by HIV and AIDS: a systematic review

Skeen

Sherr

Croome³

et al. 2017

Vulnerable Children and Youth Studies

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In addition to its contribution to child mortality, HIV/AIDS has a substantial impact on the psychosocial well-being of children across the globe and particularly in sub-Saharan Africa. We conducted a systematic review of the literature in order to identify studies that assess the effectiveness of interventions developed to improve the psychosocial well-being of children affected by HIV/AIDS, published between January 2008 and February 2016. Studies that were eligible for the review included male and/or female children under the age of 18 years of age, who had lost a parent to HIV/AIDS, were living with a parent with HIV/AIDS, or were vulnerable because of other social and economic factors and living in communities of high HIV and AIDS prevalence, including child and caregiver reports. Studies were included if they documented any intervention to improve the psychosocial well-being of children including psychological therapy, psychosocial support and/or care, medical interventions and social interventions, with psychological and/or social factors as outcomes. We identified 17 interventions to improve the psychosocial well-being of children affected by HIV/AIDS. Of these, 16 studies took place in eight different low and middle-income countries (LMIC), of which 6 were in southern and eastern Africa. One study took place in a high-income setting. Of the total, fifteen showed some significant benefits of the intervention, while two showed no difference to psychosocial outcomes as a result of the intervention. The content of interventions, dosage and length of follow up varied substantially between studies. There were few studies on children under seven years and several focused mostly on girls. Efforts to improve evaluation of interventions to improve the psychosocial well-being of children affected by HIV/AIDS have resulted in a number of new studies which met the inclusion criteria for the review. Most studies are specially designed research projects and not evaluations of existing services. We call for increased partnerships between policy-makers, practitioners and researchers in order to design evaluation studies and can feed into the growing evidence base.

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A Prospective Longitudinal Study of Mental Health Symptoms Among Perinatally HIV-Infected and HIV-Exposed but Uninfected Urban Youths

Cited by 30 publications

References 39 publications

Anxiety and depression symptoms in young people with perinatally acquired HIV and HIV affected young people in England

Anxiety and depression symptoms in young people with perinatally acquired HIV and HIV affected young people in England

Mental health challenges among adolescents living with HIV

Interventions to improve psychosocial well-being for children affected by HIV and AIDS: a systematic review

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