A Prospective Comparison of Octyl Cyanoacrylate Tissue Adhesive (Dermabond) and Suture for the Closure of Excisional Wounds in Children and Adolescents

Bernard, Laurie A.; Doyle, Julie; Friedlander, Sheila Fallon; Eichenfield, Lawrence F.; Gibbs, Neil F.; Cunningham, Bari B.

doi:10.1001/archderm.137.9.1177

Cited by 103 publications

(61 citation statements)

References 18 publications

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“…Surgical adhesives are increasingly being used in soft tissue repair as fasteners and sealants because they can be applied easily without physically injuring the tissue [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. An ideal adhesive would adhere rapidly to the tissue substrate and provide adequate strength to the joint under physiological conditions while enabling the wound to heal.…”

Section: Introductionmentioning

confidence: 99%

Adhesive strength and curing rate of marine mussel protein extracts on porcine small intestinal submucosa

et al. 2007

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An adhesive protein extracted from marine mussel (Mytilus edulis) was used to bond strips of connective tissue for the purpose of evaluating the use of curing agents to improve adhesive curing. Specifically, mussel adhesive protein solution (MAPS, 0.5 mM dihydroxyphenylalanine) was applied, with or without the curing agents, to the ends of two overlapping strips of porcine small intestinal submucosa. The bond strength of this lap joint was determined after curing for 1 h at room temperature (25°C). The strength of joints formed using only MAPS or with only the ethyl, butyl or octyl cyanoacrylate adhesives were determined. Although joints bonded using ethyl cyanoacrylate were strongest, those using MAPS were stronger than those using butyl and octyl cyanoacrylates. The addition of 25 mM solutions of the transition metal ions V 5+ , Fe 3+ and Cr 6+ , which are all oxidants, increased the bond strength of the MAPS joints. The V 5+ gave the strongest bonds and the Fe 3+ the second strongest. In subsequent tests with V 5+ and Fe 3+ solutions, the bond strength increased with V 5+ concentration, but it did not increase with Fe 3+ concentration. Addition of 250 mM V 5+ gave a very strong bond.

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Section: Introductionmentioning

confidence: 99%

Adhesive strength and curing rate of marine mussel protein extracts on porcine small intestinal submucosa

et al. 2007

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“…8 On the contrary, Bernard L et al, compared tissue adhesive and conventional suturing for lacerations and surgical wounds found that the cosmetic outcome of cutaneous excisional surgery wounds closed with standard suturing was found to be superior to that of wounds closed with octyl cyanoacrylate. 19 In this study the average Stony Brooke scar evaluation scale score in the 2-octyl cyanoacrylate group was 4.2±1.03 (95% CI: 3.907-4.49). In the suturing group the average score was 3.12±1.04 (95% CI: 2.82-3.41).…”

Section: Discussionmentioning

confidence: 51%

Comparison of conventional suturing and tissue adhesive (2-octyl cyanoacrylate) for port site skin closure in laparoscopic surgeries

2017

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“…No presente relato, como o lóbulo auricular se mostrava como zona de pele frouxa, que estava isenta dessas características, e a sua lesão mostrava-se linear, com bordas hígidas, optamos pelo uso do cianoacrilato como primeiro tratamento. O uso de cianoacrilatos para feridas de alta tensão tem sido limitado, uma vez que esse adesivo consegue força tênsil de uma sutura 5-0 2,11 . No presente relato, como o lóbulo auricular se mostrava como zona de pele frouxa que estava isenta destas características e a sua lesão mostrava-se linear com bordas hígidas, optamos pelo uso do cianoacrilato como o primeiro tratamento.…”

Section: Discussionunclassified

Reparo de fissura de lóbulo auricular usando cola cirúrgica de menor custo

Souza

Briglia²

2010

Rev. Bras. Cir. Plást. (Impr.)

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Rev. Bras. Cir. Plást. 2010; 25(4): 715-8 715Reparo de fissura de lóbulo auricular usando cola cirúrgica de menor custo Reparo de fissura de lóbulo auricular usando cola cirúrgica de menor custo Cleft earlob repair by use of low cost surgical glue RESUMO Introdução: As vantagens dos cianoacrilatos em síntese cutânea têm sido sobejamente demonstradas na literatura. Entretanto, estes produtos têm sido subutilizados no Brasil devido aos elevados custos do 2-octilcianoacrilato. Ademais, a forma mais economicamente acessível, o 2-etilcianoacrilato (ECA), tem sido pouco estudada como adesivo cutâneo. Relato do Caso: No caso descrito, os autores relatam a eficiência e as vantagens do fechamento de uma laceração de lóbulo auricular de uma criança usando o ECA de menor custo como alternativa à sutura.Descritores: Adesivos teciduais. Cianoacrilatos. Deformidades adquiridas da orelha. Orelha externa/lesões. ABSTRACT Background:The advantages of the cyanoacrylates in cutaneous synthesis have been frequently shown in the literature. However, these products have not been very used in Brazil due to the high costs of the 2-octilcyanoacrylate. Besides, the form more economically accessible, the 2-etilcyanoacrylate (ECA) has not been much studied as cutaneous adhesive. Case Report: The authors describe the efficiency and the advantages of a laceration closing of a child's earlobe using the low cost ECA as alternative to the suture.

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A Prospective Comparison of Octyl Cyanoacrylate Tissue Adhesive (Dermabond) and Suture for the Closure of Excisional Wounds in Children and Adolescents

Cited by 103 publications

References 18 publications

Adhesive strength and curing rate of marine mussel protein extracts on porcine small intestinal submucosa

Adhesive strength and curing rate of marine mussel protein extracts on porcine small intestinal submucosa

Comparison of conventional suturing and tissue adhesive (2-octyl cyanoacrylate) for port site skin closure in laparoscopic surgeries

Reparo de fissura de lóbulo auricular usando cola cirúrgica de menor custo

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