In this the second part of a 2-part ICU staffing series, we enjoin the reader to enter the multidisciplinary discussion over the broad issue of ICU staffing. Part 1 (vol. 1 no. 2, March 2010) emphasized evidence based, patient-centered staffing and outlined some challenges from a nursing and staffing perspective. The section outlined principles, standard practices and human resources concerns for the clinician, manager and ICU director. In part 2, we explore design, management and business models as well as unit operations in relation to ICU staff and ICU patients. It includes evidence behind key concepts linking ICU structure, team design and staffing. The primer encourages ICU leaders to step out of the weeds and take a walk in the woods to explore each others' perspectives and literature.