A prospective cohort study using non-invasive methods of cardiovascular assessment to compare postnatal adaptation in well late preterm and term infants

Mahoney, Liam; Álvarez, Jesús Cuéllar; Wertheim, David; Rojas-Anaya, Héctor; Aiton, Neil; Seddon, Paul; Rabe, Heike

doi:10.1016/j.earlhumdev.2022.105579

Cited by 1 publication

(1 citation statement)

References 15 publications

(17 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In low‐altitude areas, the lower the GA, the less the cardiac output, and the lower the PPI. Another cohort study 4 that used two non‐invasive cardiovascular assessments found differences in cardiovascular adaptive responses in preterm and term newborn infants. This suggested that GA may affect PPI, which was similar to our findings at low altitude.…”

Section: Altitude Groups Pre‐ductal Ppi P 95% CLmentioning

confidence: 99%

The gestational age significantly affects peripheral perfusion index value in low‐altitude areas

Hua

Zheng

Xuan³

et al. 2023

Acta Paediatrica

View full text Add to dashboard Cite

Newborn infants, especially those in the neonatal intensive care unit, tend to go through a transition period in early life including complex perfusion changes. Haemodynamic monitoring allows for early detection of diseases, thus improving outcomes and can be life-saving. A reliable modality of hemodynamic monitoring requires early, direct, non-invasive and continuous detection of irreversible damage caused by insufficient tissue perfusion and oxygenation. PPI has been embedded in the latest generation of pulse oximeters, which obtain data via a sensor attached to infants' palm or sole and emit 940 nm near-infrared light. Different tissues and blood vessels absorb different amounts of light, with the amount of light absorbed by pulsatile tissues-dynamic changes of arterial blood flow, and non-pulsatile tissues-venous blood, muscle and other tissues, being detected. The amount of light absorbed by non-pulsatile tissue is constant. PPI is the percentage of the former to the latter. 1 It reflects the real-time change of peripheral blood flow and is an evaluation of pulse intensity at specific monitoring sites. 2 In the newborn population, GA has a great impact on physiology. The early postnatal PPI values of newborns at different GAs may also be different. 1 Therefore, the range and thresholds of PPI values for detecting diseases in newborns should be modified according to different GA. 1 In addition, studies which investigated PPI were previously conducted at sea level but lacked data from other altitudes. 3

show abstract

Section: Altitude Groups Pre‐ductal Ppi P 95% CLmentioning

confidence: 99%