A Prospective 9-Month Human Clinical Evaluation of Laser-Assisted New Attachment Procedure (LANAP) Therapy

Nevins, M; Kim, Soo-Woo; Camelo, Marcelo; Martín, Ignacio Sanz; Kim, David; Nevins, Myron

doi:10.11607/prd.1848

Cited by 72 publications

(133 citation statements)

References 0 publications

Supporting

Mentioning

129

Contrasting

Order By: Relevance

“…Dr. Marc Nevins and his group at Harvard School of Dental Medicine conducted a prospective trial of eight LANAP™-treated patients with periodontally infected teeth that were scheduled for extraction. 11,12 The histologic results were presented above. They have just published the 9-Mo changes in probing depth in this cadre of patients that we can compare to the current results.…”

Section: Discussionmentioning

confidence: 99%

“…They have just published the 9-Mo changes in probing depth in this cadre of patients that we can compare to the current results. 12 We made adjustments of the LANAP™ protocol to accommodate the split-mouth design and this is the primary difference between the two groups. For the purpose of an accurate comparison the current study PD data have been resorted into the ≥ 5mm category and 0mm baseline pocket depths removed from the sample ( Table 3).…”

Section: Discussionmentioning

confidence: 99%

“…A more detailed description of the LANAP™ procedure is provided elsewhere. 5,12 Statistical analysis. Results were recorded by pocket for both probing depth and bleeding.…”

Section: Modified Widman Flap (Mwf)mentioning

confidence: 99%

“…A recent publication from this group reports probing depths at nine months post-LANAP. 12 In the DISCUSSION these data from a whole mouth LANAP™ procedure are compared to the present probing depths following LANAP™ in a split mouth design.…”

Section: Introductionmentioning

confidence: 98%

See 3 more Smart Citations

Change in clinical indices following laser or scalpel treatment for periodontitis: A split-mouth, randomized, multi-center trial

Harris¹,

Nicholson

McCarthy

et al. 2014

Lasers in Dentistry XX

View full text Add to dashboard Cite

Data are presented from a multi-center, prospective, longitudinal, clinical trial comparing four different treatments for periodontitis, (1) the LANAP™ protocol utilizing a FR pulsed-Nd:YAG laser; (2) flap surgery using the Modified Widman technique (MWF); (3) traditional scaling and root planing (SRP); and (4) coronal debridement (CD). Each treatment was randomized to a different quadrant. Fifty-one (54) subjects were recruited at five centers that included both private practice and university-based investigators. At 6-months and 12 months post-treatment the LANAP™ protocol and MWF yielded equivalent results based on changes in probing depths. The major difference observed between the two procedures was that patients reported significantly greater comfort following the LANAP™ procedure than following the MWF (P<0.001). There was greater reduction in bleeding in the LANAP™ quadrant than in the other three at both 6 and 12 months. Improvements following SRP were better than expected at 6 months and continued to improve, providing outcomes that were equivalent to both LANAP™ and MWF at 12 months. The improvement in the SRP quadrants suggests the hypothesis that an aspect of the LANAP™ protocol generated a significant, positive and unanticipated systemic (or trans-oral) effect on sub-gingival wound healing.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…A more detailed description of the LANAP™ procedure is provided elsewhere. 5,12 Statistical analysis. Results were recorded by pocket for both probing depth and bleeding.…”

Section: Modified Widman Flap (Mwf)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

See 2 more Smart Citations

Change in clinical indices following laser or scalpel treatment for periodontitis: A split-mouth, randomized, multi-center trial

Harris¹,

Nicholson

McCarthy

et al. 2014

Lasers in Dentistry XX

View full text Add to dashboard Cite

show abstract

“…The Nd:YAG has shown improvement in periodontal clinical trials with clinical parameters including a histologic assessment. 1,2,3) . The Er:YAG laser has been proposed as an alternative or adjunct to conventional mechanical periodontal therapy.…”

Section: Original Articlesmentioning

confidence: 99%

The Effect of an Er,Cr:YSGG Laser in the Management of Intrabony Defects Associated with Chronic Periodontitis Using Minimally Invasive Closed Flap Surgery. A Case Series

et al. 2016

View full text Add to dashboard Cite

Evaluation of soft‐tissue response around laser microgrooved titanium percutaneous devices

2019

View full text Add to dashboard Cite

Percutaneous devices are prone to epidermal downgrowth and sinus tract formation, which can serve as a nidus for bacterial colonization and increase the risk of periprosthetic infection. A laser microgrooved topography has been shown to limit gingival epidermal downgrowth around dental implants. However, the efficacy of this laser microgrooved topography to limit epidermal downgrowth around nongingival percutaneous devices is yet to be investigated. In this study, devices with a porouscoated subdermal component and a percutaneous post were designed and manufactured. The proximal 2 mm section of the percutaneous post were left smooth, or were textured with either a porous coating, or with the laser microgrooved topography. The smooth and porous topographies served as controls. The devices were tested in a hairless guinea pig back model, where 18 animals were randomly assigned into three groups, with each group receiving one implant type (n = 6/group). Four weeks postimplantation, the devices with surrounding soft-tissues were harvested and processed for histological analyses. Results indicated that the laser microgrooved topography failed to prevent epidermal downgrowth (23 ± 4%) around percutaneous posts in this model. Furthermore, no significant differences (p = 0.70) in epidermal downgrowth were present between the three topographies, with all the groups exhibiting similar measures of downgrowth. Overall, these findings suggest that the laser microgrooved topography may not halt downgrowth around percutaneous devices for dermal applications.

show abstract

A Prospective 9-Month Human Clinical Evaluation of Laser-Assisted New Attachment Procedure (LANAP) Therapy

Cited by 72 publications

References 0 publications

Change in clinical indices following laser or scalpel treatment for periodontitis: A split-mouth, randomized, multi-center trial

Change in clinical indices following laser or scalpel treatment for periodontitis: A split-mouth, randomized, multi-center trial

The Effect of an Er,Cr:YSGG Laser in the Management of Intrabony Defects Associated with Chronic Periodontitis Using Minimally Invasive Closed Flap Surgery. A Case Series

Evaluation of soft‐tissue response around laser microgrooved titanium percutaneous devices

Contact Info

Product

Resources

About