A propensity score‐integrated approach for leveraging external data in a randomized controlled trial with time‐to‐event endpoints
Wei‐Chen Chen,
Nelson Lu,
Chenguang Wang
et al.
Abstract:In a randomized controlled trial with time‐to‐event endpoint, some commonly used statistical tests to test for various aspects of survival differences, such as survival probability at a fixed time point, survival function up to a specific time point, and restricted mean survival time, may not be directly applicable when external data are leveraged to augment an arm (or both arms) of an RCT. In this paper, we propose a propensity score‐integrated approach to extend such tests when external data are leveraged. S… Show more
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