A Promising View of Kudzu Plant, Pueraria montana var. lobata (Willd.) Sanjappa &amp; Pradeep: Flavonoid Phytochemical Compounds, Taxonomic Data, Traditional Uses and Potential Biological Activities for Future Cosmetic Application

Intharuksa, Aekkhaluck; Sasaki, Yohei

doi:10.3390/cosmetics7010012

Cited by 22 publications

(10 citation statements)

References 36 publications

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“… 9 Whereas, P. thomsonii is more susceptible to low temperature and mainly distributes in the temperate regions of eastern and southeast Asia. 10 Morphologically, P. montana has smaller and almond-shaped leaves, thinner vines and more elongated roots than that of P. thomsonii , which possibly makes P. montana more malleable and stronger vigour. As a variety without artificial domestication, P. montana possibly contains some special resistance genes which were lost in P. thomsonii.…”

Section: Introductionmentioning

confidence: 99%

Chromosome-level and graphic genomes provide insights into metabolism of bioactive metabolites and cold-adaption of Pueraria lobata var. montana

Shang

et al. 2022

DNA Research

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Pueraria lobata var. montana (P. montana) belongs to the genus Pueraria and originated in Asia. Compared with its sister P. thomsonii, P. montana has stronger growth vigor and cold-adaption, but contains less bioactive metabolites such as puerarin. To promote the investigation of metabolic regulation and genetic improvement of Pueraria, the present study reports a chromosome-level genome of P. montana with length of 978.59 Mb and scaffold N50 of 80.18 Mb. Comparative genomics analysis showed that P. montana possesses smaller genome size than that of P. thomsonii owing to less repeat sequences and duplicated genes. A total of 6,548 and 4,675 variety-specific gene families were identified in P. montana and P. thomsonii, respectively. The identified variety-specific and expanded/contracted gene families related to biosynthesis of bioactive metabolites and microtubules are likely the causes for the different characteristics of metabolism and cold-adaption of P. montana and P. thomsonii. Moreover, a graphic genome was constructed based on 11 P. montana accessions. Total 92 structural variants were identified and most of which are related to stimulus-response. In conclusion, the chromosome-level and graphic genomes of P. montana will not only facilitate the studies of evolution and metabolic regulation, but also promote the breeding of Pueraria.

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Section: Introductionmentioning

confidence: 99%

Chromosome-level and graphic genomes provide insights into metabolism of bioactive metabolites and cold-adaption of Pueraria lobata var. montana

Shang

et al. 2022

DNA Research

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“…This plant is used in the preparation of many foods and cosmetics. In addition, this plant also has potential for biological activities such as antioxidant, antiglycation, skin generation, and melanogenesis inhibitory [ 35 ].…”

Section: Resultsmentioning

confidence: 99%

Prediction of Potential Natural Antibiotics Plants Based on Jamu Formula Using Random Forest Classifier

et al. 2022

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Jamu is the traditional Indonesian herbal medicine system that is considered to have many benefits such as serving as a cure for diseases or maintaining sound health. A Jamu medicine is generally made from a mixture of several herbs. Natural antibiotics can provide a way to handle the problem of antibiotic resistance. This research aims to discover the potential of herbal plants as natural antibiotic candidates based on a machine learning approach. Our input data consists of a list of herbal formulas with plants as their constituents. The target class corresponds to bacterial diseases that can be cured by herbal formulas. The best model has been observed by implementing the Random Forest (RF) algorithm. For 10-fold cross-validations, the maximum accuracy, recall, and precision are 91.10%, 91.10%, and 90.54% with standard deviations 1.05, 1.05, and 1.48, respectively, which imply that the model obtained is good and robust. This study has shown that 14 plants can be potentially used as natural antibiotic candidates. Furthermore, according to scientific journals, 10 of the 14 selected plants have direct or indirect antibacterial activity.

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“…The major phytoconstituents of kudzu are polyphenols, specially isoflavonoids and triterpenoids ( Figures 5& 6). [98] Pueraria montana var. lobata is considered recently as a potential therapy for alcohol abuse via various mechanisms.…”

Section: Resultsmentioning

confidence: 99%

Natural Products for the Treatment of Drug Addiction: Narrative Review

Raslan

2022

Chemistry & Biodiversity

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Drug addiction is considered a chronic disorder affecting the individual's life, his/her family and society. Up till now the treatment of drug addiction is considered a problematic issue. Synthetic drugs available for the treatment of drug addiction are few, of limited efficacy and associated with serious side effects. Therefore, there is a continuous search for better therapeutic agents for drug addiction. Natural products represent a promising source for drug addiction treatment. This review summaries drug addiction definition, its mechanism of action, its types, its diagnosis, factors affecting its development and different available approaches for its treatment especially the use of natural products. Six plants were discussed thoroughly in this review, including, Tabernanthe

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A Promising View of Kudzu Plant, Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep: Flavonoid Phytochemical Compounds, Taxonomic Data, Traditional Uses and Potential Biological Activities for Future Cosmetic Application

Cited by 22 publications

References 36 publications

Chromosome-level and graphic genomes provide insights into metabolism of bioactive metabolites and cold-adaption of Pueraria lobata var. montana

Chromosome-level and graphic genomes provide insights into metabolism of bioactive metabolites and cold-adaption of Pueraria lobata var. montana

Prediction of Potential Natural Antibiotics Plants Based on Jamu Formula Using Random Forest Classifier

Natural Products for the Treatment of Drug Addiction: Narrative Review

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