A Promising Solution to Enhance the Sensocompatibility of Biosensors in Continuous Glucose Monitoring Systems

Abstract

These results suggest that the mechanical properties of the coating are sufficient for the given application, that the coating is effective in preventing protein adsorption and blood clot formation on the sensor surface, and that the coating can be applied to membranes without hindering their glucose and oxygen transport.

Continuous Glucose Monitoring in the Subcutaneous Tissue over a 14-Day Sensor Wear Period

“…5,6 Various efforts are directed toward applying passive or active coatings to the sensor to mitigate this effect. 7,8 However, when trying to understand sensor drift in vivo, it is difficult to separate the contributing components such as instability of sensor chemistry and immune response. Because different sensor types use different materials and geometries, data from the literature cannot be used to predict the in vivo stability of a specific sensor system.…”