A promising and highly sensitive electrochemical platform for the detection of fentanyl and alfentanil in human serum

Li, Meng; Duan, Shimeng; Chen, Haiou; Zou, Fangyuan; Zhang, Genlin; Liu, Qingju; Zhang, Ruilin; Zeng, Xiaofeng; Bai, Huiping

doi:10.1007/s00604-023-05977-8

Microchim Acta

2023

DOI: 10.1007/s00604-023-05977-8

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A promising and highly sensitive electrochemical platform for the detection of fentanyl and alfentanil in human serum

Meng Li,

Shimeng Duan,

Haiou Chen

et al.

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2024

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Cited by 3 publications

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High-performance fentanyl molecularly imprinted electrochemical sensing platform designed through molecular simulations

Li,

Chen,

et al. 2024

Analytica Chimica Acta

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An ultrasensitive aptasensor for 8-hydroxy-2′-deoxyguanosine of human urine detection based on COFTAPB-DMTP@MWCNT-COOH nanocomposites and CeFeOx-C@Au@Apt nanoprobe

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et al. 2024

Microchemical Journal

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How new nanotechnologies are changing the opioid analysis scenery? A comparison with classical analytical methods

Usman,

Baig,

Nardiello

et al. 2024

Forensic Sciences Research

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Opioids such as heroin, fentanyl, raw opium, and morphine have become a serious threat to the world population in the recent past, due to their increasing use and abuse. The detection of these drugs in biological samples is usually carried out by spectroscopic and/or chromatographic techniques, but the need for quick, sensitive, selective, and low-cost new analytical tools has pushed the development of new methods based on selective nano-sensors, able to meet these requirements. Modern sensors, which utilize ‘next-generation’ technologies like nanotechnology, have revolutionized drug detection methods, due to easiness of use, their low cost, and their high sensitivity and reliability, allowing the detection of opioids at trace levels in raw, pharmaceutical, and biological samples (e.g., blood, urine, saliva, and other biological fluids). The peculiar characteristics of these sensors not only have allowed on-site analyses (in the field, at the crime scene, etc.), but they are nowadays replacing the gold standard analytical methods in the laboratory, even if a proper method validation is still required. This paper reviews advances in the field of nanotechnology and nano-sensors for the detection of commonly abused opioids, both prescribed (i.e., codeine and morphine) and illegal narcotics (i.e., heroin and fentanyl analogues).

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A promising and highly sensitive electrochemical platform for the detection of fentanyl and alfentanil in human serum

Cited by 3 publications

References 40 publications

High-performance fentanyl molecularly imprinted electrochemical sensing platform designed through molecular simulations

High-performance fentanyl molecularly imprinted electrochemical sensing platform designed through molecular simulations

An ultrasensitive aptasensor for 8-hydroxy-2′-deoxyguanosine of human urine detection based on COFTAPB-DMTP@MWCNT-COOH nanocomposites and CeFeOx-C@Au@Apt nanoprobe

How new nanotechnologies are changing the opioid analysis scenery? A comparison with classical analytical methods

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