“…We have the same question in our mind on how reliable are our hair bio element concentration in healthy and people suffering from depression [3]. Recently, however, Diah and Wong [4] have proved that the hair chemical analysis was not to be blamed for the diversity of the bio elements contents in the, what we call the hair replicates. Indeed, every hair sample is a mixed set of hair piles (and their follicles) at the different stage of their development.…”
Section: Editorialmentioning
confidence: 99%
“…Council of Canada, I studied the problem of zinc availability from milk protein and plant protein based infant formulas [4]. During that study I observed that the amount of zinc in the bones was linearly growing with the amount of zinc in the diet from zero to 12 ppm, and that after that the more addition of zinc to the diet was leveled off.…”
Section: As a Young Postdoctoral Fellow Of The National Researchmentioning
The bio elements, i.e. electrolytes, trace elements, and ultra-trace elements, nutritional status is an important indicator of human health.Herewith, we analyzed the hair bio element contents of (in decreasing
“…We have the same question in our mind on how reliable are our hair bio element concentration in healthy and people suffering from depression [3]. Recently, however, Diah and Wong [4] have proved that the hair chemical analysis was not to be blamed for the diversity of the bio elements contents in the, what we call the hair replicates. Indeed, every hair sample is a mixed set of hair piles (and their follicles) at the different stage of their development.…”
Section: Editorialmentioning
confidence: 99%
“…Council of Canada, I studied the problem of zinc availability from milk protein and plant protein based infant formulas [4]. During that study I observed that the amount of zinc in the bones was linearly growing with the amount of zinc in the diet from zero to 12 ppm, and that after that the more addition of zinc to the diet was leveled off.…”
Section: As a Young Postdoctoral Fellow Of The National Researchmentioning
The bio elements, i.e. electrolytes, trace elements, and ultra-trace elements, nutritional status is an important indicator of human health.Herewith, we analyzed the hair bio element contents of (in decreasing
“…However, the great hopes for massive using of noninvasively collected hair for bio element analysis in clinical practice and epidemiological studies 3,4 faded when the analysis of the hair replicate samples yielded an excessive dispersion of the supposedly identical hair replicates samples 5 . It was assumed that the observed variability is related to the inaccuracies of chemical analysis of hair samples until Dinh and Wong 6 showed that what was considered to be the replicate of the hair sample was in fact a non-homogenous random mixture of hair piles in their various stages of hair developmental cycle. In short, the treads of the hair sample collected from even the same head are not to be considered the identical replicates.…”
Background. There is a need for assessing personalized nutritional status of the bio elements magnesium (Mg) and calcium (Ca). Objective. We studied the Mg and Ca nutritional status by analyzing their concentrations frequency distribution in the long-term biological indicator tissue of hair. Design. Hair Mg and Ca were analyzed in 1073 apparently healthy white adult Caucasians of both sexes [734 women (♀) and 339 men (♂)] with the ICP MS. The concentrate frequency distribution data were log transformed and the nutritional status assessed with the Median Derivatives Bioassay. Results. The hair median values (µg∙g-1) were Women (♀) Mg 254 and Men (♂) Mg 137.2 whereas W (♀) Ca median was 721.4 and M (♂) Ca 492.0, respectively. Adequate nutritional status range limits arranged themselves along the linear part of the sigmoid saturation curve. These linear adequate window range limits were for women magnesium W (♀) Mg 29.7–270.6 and for men M (♂) Mg 20.5–90.2. The adequate range limits for calcium were W (♀) Ca 487.7–4456.8 and M (♂) Ca 26.1–816.4. The bone seeking bio elements Ca, Mg, and Sr showed the same increasing affinity for women hair deposition, whereas the major cellular electrolytes of sodium and potassium were almost imperceptibly higher in men than women. Conclusions. Women hair incorporates Mg and Ca at about 2.5 times higher rate than men hair. The hair Median Derivatives Bioassay is a convenient painless way to assess and monitor the personalized dietary nutritional status of Mg and Ca in women and men.
“…For a long time use of hair bio element (bioinorganic elements) analysis in clinical practice was considered controversial, because the analyses of the replicate hair samples in different laboratories were discrepant [3]. Today, we know that there is no identical hair sample replicate, even if they came from the same head, since the collected hair sample is a mixture of hair piles in their distinct follicular growth cycle phase [4].…”
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