A prevalence study of celiac disease in persons with Down syndrome residing in the United States of America

Pueschel, SM; Romano, Corrado; Failla, Pinella; Barone, Concetta; Pettinato, Rosa; Chiodo, A Castellano; Plumari, DL

doi:10.1111/j.1651-2227.1999.tb00188.x

Cited by 40 publications

(25 citation statements)

References 22 publications

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“…De acordo com Pueschel et al 13 , a força muscular do portador da SD tende a melhorar à medida que ganha mais idade. As médias de idade apresentadas no presente estudo encontram-se bem próximas daquela encontrada por Godoy e Barros 21 , que foi de 27,82±6,63 anos para ambos os sexos.…”

Section: Discussionunclassified

Estudo comparativo da força de preensão manual em portadores de síndrome de Down

Silva¹,

Silva²,

Filho³

et al. 2009

Fit Per J

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Silva NM, Silva SF, Gomes Filho A, Fernandes Filho J. Estudo comparativo da força de preensão manual em portadores de síndrome de Down. Fit Perf J. 2009 set-out;8(5):383-8. RESUMOIntrodução: A força de preensão manual tem se mostrado importante, por constituir um indicador relevante para a avaliação da força dos sujeitos portadores da síndrome de Down. O objetivo do estudo foi comparar a força de preensão manual entre os sexos masculino e feminino, e entre os lados direito e esquerdo de portadores da síndrome de Down (SD), das cidades de Itaperuna e Bom Jesus do Itabapoana, no estado do Rio de Janeiro. Materiais e Métodos: Neste estudo comparativo de corte transversal, foram investigados 28 sujeitos portadores da SD, moderadamente ativos, sendo 12 do sexo feminino com idade entre 14 e 38 anos (24,08±6,77) e 16 do sexo masculino com idade entre 14 e 44 anos (27,13±8,83). Todos os sujeitos estavam matriculados na Associação dos Pais e Amigos dos Excepcionais de seus respectivos municípios. A força muscular foi avaliada pela dinamometria com o handgrip. Resultados: A análise de variância two-way revelou diferença significativa (p<0,05) entre os sexos (masculino versus feminino), nas mãos direita (p=0,001) e esquerda (p=0,001), sendo os maiores valores encontrados nos homens. Discussão: Os portadores de SD do sexo masculino da amostra têm valores médios de força isométrica de preensão manual superiores aos indivíduos do sexo feminino, tanto na mão direita quanto na esquerda. PALAVRAS-CHAVESíndrome de Down; Força Muscular; Força da Mão; Dinamômetro de Força. The strength of manual handgrip has showed to be important for constituting a relevant indicator to assess the strength of the subjects carrying Down syndrome. The objective of this study was to compare the strength of the manual handgrip between left and right hands of men and women carriers of the Down syndrome (DS), in the cities of Itaperuna and Bom Jesus do Itabapoana, in the state of Rio de Janeiro. Materials and Methods: In this comparative study of transversal cut, 28 subjects, all carriers of DS, moderately active, 12 of whom were females aging between 14 and 38 years (24.08±6.77) and 16 males aging between 14 and 44 years (27.13±8.83) were investigated. All subjects were enrolled in Associação dos Pais e Amigos dos Excepcionais in their respective counties. Muscle strength was evaluated by dynamometry with the handgrip. Results: The analysis of the two-way variant showed significant difference (p<0.05) between genders (male versus female) on the right (p=0.001) and left hand (p=0.001), with higher values found in the male gender. Discussion: The male bearers of DS showed an average of the isometric strength of the handgrip superior to the female subjects in both right and left hands.

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Section: Discussionunclassified

Estudo comparativo da força de preensão manual em portadores de síndrome de Down

Silva¹,

Silva²,

Filho³

et al. 2009

Fit Per J

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“…La prevalencia de enfermedad celíaca (EC) varía entre 5 y 15% 24,25 , y hasta un 50% de los casos pueden presentarse en forma atípica 26 . Aún hay discusión respecto a la utilidad del tamizaje para EC en pacientes asintomáticos.…”

Section: Problemas Gastrointestinalesunclassified

Recomendaciones de cuidados en salud de personas con síndrome de Down: 0 a 18 años

2013

Rev. méd. Chile

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“…The very high incidence of celiac disease in Down's syndrome patients (16.9%; 19%) reported by Swedish authors [23,29] could have been related to the higher incidence of celiac disease in the general Swedish population [16,17] and to the criteria used by the authors, which were inconsistent with the current criteria of celiac disease diagnosis. Studies conducted on more numerous, and therefore more reliable, groups of 105 to 1202 patients show an estimated incidence of celiac disease in Down's syndrome patients of 1% to 6.3% [21,24,25,30,32,34,41,42,44]. In the analysis mentioned above the study of Goldacre et al [41] was a result of a retrospective analysis of medical records of 1453 patients Down's syndrome from the Oxford region from the years 1963-1999.…”

Section: Ema -Anti-endomysial Antibodies Aga -Anti-gliadin Antibodiementioning

confidence: 99%

“…The published studies about the incidence of celiac disease in Down's syndrome patients utilized different criteria of patient selection (Table II), and thus the study groups are heterogeneous and the results are A Au ut th ho or r, , d da at te e, , c co ou un nt tr ry y S Se el le ec ct ti io on n c cr ri it te er ri ia a o of f p pa at ti ie en nt ts s w wi it th h D Do ow wn n' 's s s sy yn nd dr ro om me e [22,30,31,35,36,38,[42][43][44]; there are few studies on the incidence of celiac disease in Down's syndrome patients conducted on the scale of a large region or country [32,39,40]. The only available multi-center study assessing the incidence of celiac disease, conducted on a group of Down's syndrome patients in a number that complies with the requirements of an epidemiological study, was performed by an Italian group.…”

Section: Ema -Anti-endomysial Antibodies Aga -Anti-gliadin Antibodiementioning

confidence: 99%

Are Down’s syndrome patients a risk group for celiac disease?

Nowak-Oczkowska¹,

Szaflarska-Popławska²,

Soroczyńska-Wrzyszcz³

2013

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K Ke ey y w wo or rd ds s: : celiac disease, Down's syndrome, incidence, screening. S Sł ło ow wa a k kl lu uc cz zo ow we e: : choroba trzewna, zespół Downa, częstość występowania, badania przesiewowe.A Ad dd dr re es ss s f fo or r c co or rr re es sp po on nd de en nc ce e: : Department and Clinic of Pediatrics, Allergology, and Gastroenterology, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, 9 Marii Skłodowskiej-Curie, 85-094 Bydgoszcz, Poland, phone: +48 52 585 48 50, fax: +48 52 585 40 86, e-mail: klped@cm.umk.pl Review paper/Artykuł poglądowy AbstractCeliac disease is a genetically determined enteropathy caused by permanent gluten intolerance. The factors considered as responsible for celiac disease are genetic and environmental factors, as well as auto-immunological processes which lead to chronic inflammation. There are reports in the literature that indicate co-occurrence of celiac disease with many diseases, and one of the reported risk groups of celiac disease is patients with the most frequent chromosome abnormalityDown's syndrome. Many societies and authors recommend screening of this group. StreszczenieCeliakia jest genetycznie uwarunkowaną enteropatią spowodowaną trwałą nietolerancją glutenu. Wśród czynników odpowiedzialnych za ujawnienie choroby trzewnej wymienia się czynniki genetyczne, środowiskowe oraz procesy autoimmunologiczne prowadzące do przewlekłych stanów zapalnych. W piśmiennictwie opisuje się współistnienie choroby trzewnej z wieloma jednostkami chorobowymi, a za jedną z grup ryzyka rozwoju celiakii uznaje się najczęstszą aberrację chromosomalną, jaką jest zespół Downa. Wiele towarzystw i autorów rekomenduje przeprowadzanie badań przesiewowych w tej grupie pacjentów.

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A prevalence study of celiac disease in persons with Down syndrome residing in the United States of America

Cited by 40 publications

References 22 publications

Estudo comparativo da força de preensão manual em portadores de síndrome de Down

Estudo comparativo da força de preensão manual em portadores de síndrome de Down

Recomendaciones de cuidados en salud de personas con síndrome de Down: 0 a 18 años

Are Down’s syndrome patients a risk group for celiac disease?

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