Blood biomarker profiling, using data from blood tests beyond its traditional medical diagnostic context, is a practice that is becoming more common and accessible in an health and athletic setting. Blood profiling may cast light on macro- and micronutrient deficiencies or insufficiencies that can cause increased risk of illness and injury or be directly detrimental to exercise performance. Professional dancing commonly invokes high training loads and reduced quality of nutritional intake alongside high injury rates and self-reported ‘fatigue’. Objective blood biomarker measurements may be able to assist dance companies, artistic health care and individual professionals in the implementation of interventions to prevent and avoid injury, illness and/or ‘burnout’. For example; altered metabolic hormones may indicate an energy deficiency for which nutritional support can be provided; identifying iron deficiency can inform a supplementation protocol and subsequently benefit wellbeing and performance. This review aims to provide insights into the ‘why,’ ‘how’ and ‘what’ for blood biomarker profiling to benefit dancers’ health, wellbeing, and performance.