Abstract:We describe protein sequences for a uromodulin-like larval glycoprotein (LGP) from 21 species of galaxiid fishes, with a MRCA about 30 Ma. These have been derived from both genomic DNA and cDNA, by conventional and Roche 454 sequencing.LGP shows a fast rate of evolution and an exceptionally strong signal of positive selection over the entire coding region, as evidenced byAcross all sequences, 182/336 (54 %) of residues are variable; many substitutions are profound/nonconservative and include in-frame indels. G… Show more
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