A preliminary study of factors influencing perception of menstrual blood loss volume

Fraser, Ian S.; McCarron, G; Markham, Robert

doi:10.1016/0002-9378(84)90123-6

Cited by 222 publications

(114 citation statements)

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“…In a study in women with iron-deficiency anemia because of menorrhagia, only 15% described their periods as heavy [14]. At the other end of the spectrum, it has been reported that 26-38% of women complaining of heavy periods had objective menstrual losses of less than 80 ml per cycle [15]. In our study, we found that 26.5% of women complaining of menorrhagia had normal blood hemoglobin levels before surgery.…”

Section: Discussionsupporting

confidence: 62%

The role of laparoscopic dissection of the uterine artery in the surgical treatment of fibroid-related menorrhagia: a pilot study

et al. 2004

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This pilot study assessed the outcome, tissue trauma, clinical improvement and reduction in size of fibroids following laparoscopic dissection of the uterine artery (LDUA) in fibroid-related menorrhagia. Fiftythree patients with complete records were included in the prospective clinical study. Before LDUA, and 3 and 6 months following the procedure, ultrasonography or MRI was done to measure the size of the uterus and dominant fibroid. Blood samples for hemoglobin and assay of marker inflammatory response and tissue trauma were taken preoperatively on the 1st and 3rd postoperative days. All patients underwent successful LDUA using ultrasonically activated shears without intra-operative complications. Fifty (96.2%) laparoscopically treated patients with fibroids who subsequently experienced improvement in menorrhagia and anemia are described. The LDUA procedure can be completed within 30-40 min with only minimal blood loss and a short hospital stay if performed by experienced surgeons. Our study results show that single laparoscopic dissection of the uterine artery performed with ultrasonic technique is associated with an insignificant stress response. The average reductions in the uterine volume and dominant fibroid volume were 36.6 and 57.9% at 6 months after surgery, respectively. Four women conceived within 1 year, and their pregnancies were without complications during gestation.

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Section: Discussionsupporting

confidence: 62%

The role of laparoscopic dissection of the uterine artery in the surgical treatment of fibroid-related menorrhagia: a pilot study

et al. 2004

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Section: Introductionmentioning

confidence: 99%

“…This type of iron deficiency is often insidious as women have great difficulty in assessing the amount of their menstrual losses (7)(8)(9), and they may lose abnormally high amounts of blood during each menstruation period without being aware that the loss is excessive. In addition, neither the duration of menses nor the number of pads used is indicative of the actual blood loss (7). In the clinic, there are two main reasons why it is difficult to discern between 'normal' and 'abnormal' menstrual blood loss: firstly, the definition of 'normal' loss is largely subjective (7); and secondly, there are no simple and easily reproducible methods to measure blood losses.…”

Section: Introductionmentioning

confidence: 99%

Iron-dependent erythropoiesis in women with excessive menstrual blood losses and women with normal menses

et al. 2013

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In women of fertile age, iron loss consequent to excessive menstrual discharge is by far the most frequent cause of iron-deficient anemia. However, the relationship between menstrual discharge and iron loss is poorly understood. In this prospective study, total menstrual and iron losses were assayed in a large cohort of non-anemic women and women with excessive menstrual blood losses (menorrhagia) in order to provide data useful for intervention. One hundred and five Caucasian women aged 20-45 years were recruited. Blood cell count and serum ferritin (SF) levels were determined in each case before menses. Menstrual Fluid Losses (MFL) were determined using a standardized pads' weight method. Hematin concentration was assayed by a variant of the Alkaline Hematin Method from which iron concentration was calculated. Mean SF levels were 36.2 (range 8.6-100) ng/ml in healthy women and 6.4 (range 5-14) ng/ml in patients with menorrhagia. Median values of iron lost/cycle were 0.87 mg in healthy women and 5.2 mg in patients with menorrhagia (ranges: 0.102-2.569 and 1.634-8.665 mg, respectively, p<0.001). In women with menorrhagia, iron lost/cycle strongly correlated (0.789, p<0.001) with MFL. In conclusion, healthy women with normal menses lose, on average, 1 mg iron/cycle. Average iron losses in patients with menorrhagia are, at least in our cohort, on average, 5-6 times higher than normal. Most women with menorrhagia had totally depleted iron stores. Indirect, quantitative evaluation of iron lost with menses may be useful to assess the risk of developing iron-deficient anemia in individual patients. 3 IntroductionIron is a vital element of metabolism, with the most obvious and known role played in erythropoiesis, and important functions in other intracellular processes in all tissues of the body. The uptake of iron is finely regulated (1). For physiologic iron losses, no known mechanisms of maintaining iron homeostasis have been identified, and losses appear to be related mainly to cell exfoliation (2).

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“…При этом выраженность анемии не является обязательным критерием тяжелого АМКПП. Основ-ным компонентом тяжелого АМКПП является вы-раженный физический и эмоциональный диском-форт пациентки [3,6,10].…”

Section: понятие регулярности менструаций у современных подростковunclassified

Abnormal uterine bleeding in adolescent (a review)

Sibirskaya¹,

Adamyan²,

Loginova³

et al. 2015

Probl. reprod.

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A preliminary study of factors influencing perception of menstrual blood loss volume

Cited by 222 publications

References 10 publications

The role of laparoscopic dissection of the uterine artery in the surgical treatment of fibroid-related menorrhagia: a pilot study

The role of laparoscopic dissection of the uterine artery in the surgical treatment of fibroid-related menorrhagia: a pilot study

Iron-dependent erythropoiesis in women with excessive menstrual blood losses and women with normal menses

Abnormal uterine bleeding in adolescent (a review)

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