A Preliminary Report Requiring Continuation of Research to Confirm Fallopian Tube Adenocarcinoma: A Non-Experimental, Non-Randomized, Cross-Sectional Study

Abstract

BackgroundTransvaginal ultrasound has fair characteristics, and pathology is an invasive technique for fallopian tube tumor diagnosis. Magnetic resonance images have better intra- and inter-observer reliabilities for detection of primary fallopian tube malignant tumor(s) than the other diagnostic modalities. The purpose of this study was to investigate parameters of different types of magnetic resonance images for women with fallopian tube adenocarcinoma and to compare these parameters with the FIGO grading system to improve the accuracy of diagnosis and prognosis.Material/MethodsA total of 121 women who had clinically-proven fallopian tube adenocarcinoma were included in this cross-sectional study. A 3.0 T magnetic resonance images system was used for spin-lattice relaxation-weighted (T1WI), spin-spin relaxation-weighted (T2WI), diffusion-weighted, (DWI), and apparent diffusion coefficient (ADC) images. ANOVA following Tukey post hoc tests and Spearman rank correlation were performed at 99% confidence level.ResultsAxial T1WI, axial T2WI, and axial DWI, were provided low, intermediate, and high fluid signal intensity, respectively, for a tumor. Sagittal T1WI showed contrast uptake by the mass with necrosis. Sagittal T2WI showed a solid mass with well-defined walls. Sagittal DWI showed restriction to diffusion. ADC values were significantly higher for FIGO grade 1 women than for FIGO grade 3 women (p<0.0001, q=16.591). The Spearman correlation coefficient was 0.1012 between mean ADC and FIGO grading.ConclusionsWe recommend that magnetic resonance images be included in the FIGO guideline for grading of malignancies in the female genital tract.

18-F fluorodeoxyglucose positron emission tomography/computed tomography findings of bilateral primary fallopian tube carcinoma and metastasis to the uterus: a case report and literature review

“…A previous study showed that apparent diffusion coefficient values were significantly higher in women with FIGO grade 1 than in women with FIGO grade 3 (p < 0.0001, q = 16.591), and the Spearman correlation coefficient was 0.1012 between the mean apparent diffusion coefficient and FIGO grading. 9 However, in our case, the uterine lesion was ignored by physicians in the initial diagnosis because it was small, and it was only observed in one slice of tomographic images. According to the FIGO guideline, if there are uterine or ovarian metastases, the staging will change.…”

“…Several previous studies 9 , 10 have described the MRI findings of PFTC as a sausage-shaped adnexal mass or a multilocular cystic mass with a cog-and-wheel appearance, and the solid portion shows high intensity on diffusion-weighted images. There has even been a suggestion to include MRI in the International Federation of Gynecology and Obstetrics (FIGO) guideline for grading of malignancies in the female genital tract.…”

Practical Means of Preoperative Diagnostics of Primary Fallopian Tube Cancer

“…Literature data suggest that magnetic resonance imaging (MRI) and positron emission tomography (PET) are often used for PFTC diagnostics [1,22,23]. According to some authors these methods not only visualize a tumor and its structure, but unlike USS, allow to recognize fine details of contrast, of hydrophilic and chemical specifics of tissues, to identify tumor infiltrates, their borders and metastases in regional lymph nodes [23][24][25]. There are even suggestions to include MRI into FIGO guidelines as a compulsory diagnostic procedure for PFTC [24].…”

Primary Fallopian Tube Cancer: A Literature Review

“…In contrast to sonography, MRI, in addition to anatomical features, allows recognition of fine details of contrast, hydrophilicity, and chemical features of the tumor and detection of metastases in the lymph nodes. Some authors consider it necessary to include in FIGO clinical protocols as a mandatory method of examination when FTC is suspected [31].…”