A Preliminary Investigation of Laparoscopic Fundoplication Treatment on Gastroesophageal Reflux Disease-related Respiratory Symptoms

Zhang, Chengchao; Wang, Zhonggao; Wu, Ji-Min; Lai, Yungang; Ji, Feng; Gao, Xiang; Hu, Zhiwei; Zhu, Guang-Chang; Ning, Yanzhe; Li, Zhitong; Li, Hong; Zhao, Jing

doi:10.1097/sle.0b013e3182628913

Cited by 15 publications

(13 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Postoperative follow‐up was accomplished using outpatient visits and telephone interviews. A 6‐point scale ranging was applied to assess the level of wheezing, heartburn, regurgitation, cough and chest pain according to the Reflux Disease Questionnaire, as applied in the previously published studies …”

Section: Materals and Methodsmentioning

confidence: 99%

“…A 6-point scale ranging was applied to assess the level of wheezing, heartburn, regurgitation, cough and chest pain according to the Reflux Disease Questionnaire, as applied in the previously published studies. 17,18 The medication independence and patient's satisfaction after LNF and LNF-HHR were evaluated as well. The assessment was conducted through a questionnaire survey on the patients' subjective feeling regarding the surgical success, which was graded as follows: 'excellent' (complete resolution of symptoms), 'good' (symptoms occurring monthly or less frequently), 'fair' (symptoms occurring weekly or less frequently) or 'poor' (symptoms occurring daily or more often, or as severe as prior to treatment).…”

Section: Follow-up and Outcome Measuresmentioning

confidence: 99%

See 1 more Smart Citation

Contribution of hiatal hernia to asthma in patients with gastroesophageal reflux disease

Han

et al. 2017

Clinical Respiratory J

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Materals and Methodsmentioning

confidence: 99%

Section: Follow-up and Outcome Measuresmentioning

confidence: 99%

Contribution of hiatal hernia to asthma in patients with gastroesophageal reflux disease

Han

et al. 2017

Clinical Respiratory J

Self Cite

View full text Add to dashboard Cite

show abstract

“…Between December 2013 and December 2015, 136 consecutive patients with symptomatic HH were considered for inclusion in this study. Patients were eligible for enrollment in this study if they had persistent symptoms despite daily use of proton-pump inhibitors (omeprazole 20 mg twice a day) for at least 3 months before surgery 15 . Patients were excluded if they had history of previous esophagogastric surgery, achalasia, Zollinger-Ellison syndrome, or malignant tumor.…”

Section: Methodsmentioning

confidence: 99%

Role of fundoplication in treatment of patients with symptoms of hiatal hernia

Han

et al. 2019

Sci Rep

Self Cite

View full text Add to dashboard Cite

Gastroesophageal reflux disease (GERD) is often associated with hiatal hernia (HH). However, the need for fundoplication during hiatal hernia repair (HHR) remains controversial. The objective of this study was to evaluate the effect of HHR with concomitant laparoscopic Nissen fundoplication (HHR-LNF) in HH patients. A total of 122 patients with symptomatic HH were randomized to receive either HHR (n = 61) or HHR-LNF (n = 61). The measures of evaluating outcomes included DeMeester scores (DMS), complications, Reflux Diagnostic Questionnaire and patients’ satisfaction 24 months following surgery. Despite comparable values in both groups at randomization, the DMS, total numbers of reflux episodes and percentage of time with pH < 4 were significantly higher in HHR group than in HHR-LNF group ( P = 0.017, P = 0.002 and P = 0.019, respectively) at 6 months after surgery. One months postoperatively, complications were higher in the HHR-LNF group than in the HHR group (all P < 0.001), and there was no difference between the two groups at 6 months. By the end of the 2-year follow-up, HHR-LNF group showed a significantly lower reflux syndrome frequency-intensity score and greater percentage of satisfaction compared with HHR group (all P < 0.001). Laparoscopic HHR should be combined with a fundoplication in GERD patients with HH. HHR-LNF is safe and effective, not only improve reflux-related symptom, but also reduce the incidence of complications.

show abstract

“…72 Concern about using antireflux surgery in extraesophageal reflux is a high risk-to-benefit ratio using this treatment option given the lack of robust evidence for its benefit. Most surgical data in chronic cough, [110][111][112] LPR, [113][114][115][116][117][118][119][120][121] and asthma 39,72,[122][123][124][125][126][127] are uncontrolled, retrospective, and suffer from small sample sizes. Despite enthusiasm from observational and case series reporting improvement of extraesophageal reflux symptoms, most surgeons shy away from offering fundoplication to patients with extraesophageal reflux symptoms without typical heartburn and/or regurgitation.…”

Section: Surgical Therapymentioning

confidence: 99%

Extraesophageal Symptoms and Diseases Attributed to GERD: Where is the Pendulum Swinging Now?

Vaezi

Katzka

Zerbib

2018

Clinical Gastroenterology and Hepatology

View full text Add to dashboard Cite

The purpose of this review is to outline the recent developments in the field of extraesophageal reflux disease and provide clinically relevant recommendations. The recommendations outlined in this review are based on expert opinion and on relevant publications from PubMed and EMbase. The Clinical Practice Updates Committee of the American Gastroenterological Association proposes the following recommendations: Best Practice Advice 1: The role of a gastroenterologist in patients referred for evaluation of suspected extra esophageal symptom is to assess for gastroesophageal etiologies that could contribute to the presenting symptoms. Best Practice Advice 2: Non-GI evaluations by ENT, pulmonary and/or allergy are essential and often should be performed initially in most patients as the cause of the extraesophageal symptom is commonly multifactorial or not esophageal in origin. Best Practice Advice 3: Empiric therapy with aggressive acid suppression for 6-8 weeks with special focus on response of the extraesophageal symptoms can help in assessing association between reflux and extraesophageal symptoms. Best Practice Advice 4: No single testing methodology exists to definitively identify reflux as the etiology for the suspected extra esophageal symptoms. Best Practice Advice 5: Constellation of patient presentation, diagnostic test results and response to therapy should be employed in the determination of reflux as a possible etiology in extra esophageal symptoms. Best Practice Advice 6: Testing may need to be off or on proton pump inhibitor (PPI) therapy depending on patients' presenting demographics and symptoms in assessing the likelihood of abnormal gastroesophageal reflux. A. On therapy testing may be considered in those with high probability of baseline reflux (those with previous esophagitis, Barrett's esophagus or abnormal pH). B. Off therapy testing may be considered in those with low probability of baseline reflux with the goal of identifying moderate to severe reflux at baseline. Best Practice Advice 7: Lack of response to aggressive acid suppressive therapy combined with normal pH testing off therapy or impedance-pH testing on therapy significantly reduces the likelihood that reflux is a contributing etiology in presenting extraesophageal symptoms. Best Practice Advice 8: Surgical fundoplication is discouraged in those with extra esophageal reflux symptoms unresponsive to aggressive PPI therapy. Best Practice Advice 9: Fundoplication should only be considered in those with a mechanical defect (e.g., hiatal hernia), moderate to severe reflux at baseline off PPI therapy who have continued reflux despite PPI therapy and have failed more conservative non-GI treatments.

show abstract

A Preliminary Investigation of Laparoscopic Fundoplication Treatment on Gastroesophageal Reflux Disease-related Respiratory Symptoms

Abstract: LNF can be an effective means for treating RSs in patients with GERD.

Cited by 15 publications

References 16 publications

Contribution of hiatal hernia to asthma in patients with gastroesophageal reflux disease

Contribution of hiatal hernia to asthma in patients with gastroesophageal reflux disease

Role of fundoplication in treatment of patients with symptoms of hiatal hernia

Extraesophageal Symptoms and Diseases Attributed to GERD: Where is the Pendulum Swinging Now?

Contact Info

Product

Resources

About