A Preliminary Evaluation of a Dual Crystal Positron Camera

Holte, S.; Ostertag, H.; Kesselberg, M.

doi:10.1097/00004728-198707000-00026

Cited by 29 publications

(6 citation statements)

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“…Image resolution in axial direction used in these studies was 8±11 mm FWHM (full width at half maximum) per slice. Image reconstruction was performed by OSEM (ordered subset expectation maximization) in time intervals of 30 min [32].…”

Section: Methodsmentioning

confidence: 99%

Chances and Shortcomings of Adenovirus-Mediated ATP7B Gene Transfer in Wilson Disease: Proof of Principle Demonstrated in a Pilot Study with LEC rats

Ha-Hao¹,

Merle²,

Hofmann³

et al. 2002

Z Gastroenterol

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Section: Methodsmentioning

confidence: 99%

Chances and Shortcomings of Adenovirus-Mediated ATP7B Gene Transfer in Wilson Disease: Proof of Principle Demonstrated in a Pilot Study with LEC rats

Ha-Hao¹,

Merle²,

Hofmann³

et al. 2002

Z Gastroenterol

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“…Die Natriumiodid-Kristalle, die heutzutage immer noch in Singlephotonen-Emissionscomputertomografie (SPECT)-Geräten verbaut sind, wurden in der frühen Entwicklung der PET durch Kristalle aus Bismuthgermanat (BGO), Bi 4 Ge 3 O 12 , abgelöst [8]. Hierauf folgten Gadoliniumorthosilicat, Gd 2 SiO 5 (Ce), [9] sowie, seltener verwendet, Bariumfluorid, BaF 2 , und Lanthanumbromid, LaBr 3 . PET-Szintilationskristalle der aktuellen Gerätegenerationen sind häufig aus Lutetium-Oxyorthosilicat (LSO) (auch: LBS: Lutetium basiertes Szintillatormaterial) oder Lutetium-Yttrium-Oxyorthosilicat (LYSO) aufgebaut.…”

Section: Detektortechnologieunclassified

Digitale Positronenemissionstomografie – Entwicklung, Detektortechnologie und Perspektiven

Kazek

Jentzen

Seifert

et al. 2022

Angewandte Nuklearmedizin

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ZusammenfassungDieser Übersichtsartikel präsentiert die Entwicklung und den technischen Fortschritt der Positronenemissionstomografie (PET) hin zum digital arbeitenden PET-System (dPET). Der Fokus liegt hierbei auf den PET-Hardwarekomponenten zur Detektierung sowie Verarbeitung und Ortung des Signals zur klinischen Bildgebung. Es werden technische Unterscheidungen und Vorteile der dPET-Systeme gegenüber konventionellen PET-Systemen aufgezeigt. Dazu zählen zum Beispiel größere Detektorflächen mit sehr empfindlichen und kompakten Photodetektorsystemen in Verbindung mit einer verbesserten Elektronik zur schnellen Berechnung der Orts-, Zeit- und Energieauflösungen der Signale. Die daraus neu erschlossenen Anwendungsbereiche und Perspektiven in der dPET-Bildgebung werden zusätzlich thematisiert.

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“…This technology was first replaced by Bismuth Germinate (BGO) crystals (Bi 4 Ge 3 O 12 ) introduced in 1973 [79], chosen mainly because of its higher efficiency at 511 keV. Gadolinium Oxyorthosilicate (GSO) (Gd 2 SiO 5 ) is another popular scintillator used on commercial PET scanners [33], but the current materials of choice are Lutetium Oxyorthosilicate (LSO) crystals (Lu 2 SiO 5 ) [53] and Cerium-doped Lutetium Yttrium Orthosilicate (LYSO) crytals (Lu 2(1-x) Y 2x SiO 5 :Ce).…”

Section: Hardware Innovationsmentioning

confidence: 99%

Advances in Technological Design to Optimize Exposure and Improve Image Quality

Gutiérrez

Zaidi

2013

Radiological Safety and Quality

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Multimodality imaging is playing a key role in the clinical management of patients in routine diagnosis, staging, restaging and assessment of response to treatment, surgery and radiation therapy planning of malignant diseases. The complementarity between anatomical (CT and MRI) and functional/molecular (SPECT and PET) imaging modalities is now well recognized and the role of fusion imaging is widely used as a central piece of the general tree of clinical decision making. Moreover, dual-modality imaging technologies including SPECT/CT, PET/CT and nowadays PET/MR represent the leading component of a modern healthcare facility. There have been significant advances in data acquisition along with innovative approaches to image reconstruction and processing with the aim to improve image quality and diagnostic information. However, CT procedures involve relatively high doses to the patient, which triggered many initiatives to reduce the delivered dose particularly in paediatric practice.This chapter discusses the state-of-the-art developments and challenges of multimodality medical imaging technologies and dose reduction strategies. Future opportunities and the challenges limiting their adoption in clinical and research settings will also be addressed.

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A Preliminary Evaluation of a Dual Crystal Positron Camera

Cited by 29 publications

References 0 publications

Chances and Shortcomings of Adenovirus-Mediated ATP7B Gene Transfer in Wilson Disease: Proof of Principle Demonstrated in a Pilot Study with LEC rats

Chances and Shortcomings of Adenovirus-Mediated ATP7B Gene Transfer in Wilson Disease: Proof of Principle Demonstrated in a Pilot Study with LEC rats

Digitale Positronenemissionstomografie – Entwicklung, Detektortechnologie und Perspektiven

Advances in Technological Design to Optimize Exposure and Improve Image Quality

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