A pregnane ester oligoglycoside from Oxystelma esculentum

Trivedi, Rashmi; Khare, Anakshi; Khare, Maheshwari P.

doi:10.1016/0031-9422(89)80211-0

Cited by 11 publications

(3 citation statements)

References 15 publications

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“…Velutinol A has anti-bradykinin and anti-inflammatory activity (Calixto et al, 1988a;1991a,b). The structure of velutinol comprises a novel pregnane skeleton, and steroids of this class are commonly encountered in Apocinaceae Chen et al, 1987) as well as Asclepiadaceae (Bando et al, 1980;Sethi et al, 1988;Trivedi et al, 1989;Zhang et al, 1985) and Meliaceae (Nakanishi et al , 1988). Isolation of velutinol A.…”

Section: Introductionmentioning

confidence: 99%

The structure of velutinol A, an anti‐inflammatory compound with a novel pregnane skeleton

Yunes

Pizzolatti

Santana

et al. 1993

Phytochemical Analysis

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Section: Introductionmentioning

confidence: 99%

The structure of velutinol A, an anti‐inflammatory compound with a novel pregnane skeleton

Yunes

Pizzolatti

Santana

et al. 1993

Phytochemical Analysis

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“…Column chromatography of the chloroform extract using chloroform: methanol (24:1) as eluent afforded oxysine, a triglycoside of calogenin. [11] A pregnane glycoside Esculentin was also isolated from the roots.…”

Section: General Chemical Analysismentioning

confidence: 99%

A Complete Review on Oxystelma esculentum R. Br.

Pandya

Anand

2011

Pharmacognosy Journal

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Many plants which are found commonly and are mentioned in texts of traditional Indian medicine have not been investigated thoroughly. It is necessary to conduct systematic evaluation, standardization, documentation and patenting of these plants. Oxystelma esculentum R. Br. (Family-Asclepiadaceae), commonly known as 'Jaldudhi', is one such plant which has not been studied sufficiently. It has many potential therapeutic uses which are of vital importance in curing the diseases of the modern world like cancer, hepatitis, kidney disorders, stress-related disorders and microbial infections. It contains two very important classes of phytoconstituents: cardenolides and pregnane glycosides, which are easily obtained from this plant and can act as precursors of many therapeutically important compounds. the study of this plant will be important in the future for bioactivity-guided fractionation of medicinal phytoconstituents, for conducting pre-clinical or clinical trials and for preparing formulations or semi-synthetic compounds. the present review, based on an extensive literature search of reputed books, scientific websites and high-impact journals, sheds light on the research done on this plant so far, thereby providing informative guidelines regarding the work that can be done in the future.

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“…The configuration of the sugar was determined from the large coupling constant (J = 6 Hz) of the anomeric proton, which suggested the presence of β-oleandropyranoside in 4 Mild acid hydrolysis [19] of 7 (0.05 N H 2 SO 4 in dioxane) afforded a genin identified as calogenin [20] and two sugars identified as D-digitoxose [13] and L-diginose [21] (mp, mmp, TLC, PC, [α] D ). The sugars were further characterized by preparing their known derivatives, D-digitoxono acid phenyl hydrazide [13] for D-digitoxose and L-diginonic acid phenyl hydrazide [21] ] could be interpreted as resulting from the fragment sequence common to 2,6-dideoxy hexoses [22].…”

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Three Pregnane Glycosides from Pergularia Pallida

Srivastava

Khare

2007

Natural Product Communications

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Three new pregnane glycosides designated as pergulinine, pallicine and pallicinine have been isolated from the chloroform soluble extract of Pergularia pallida. On the basis of chemical and spectroscopic evidence their structures were established as drevogenin P-3-O-α-L-rhamnopyranosyl-(1→4)-O-β-D-cymaropyranoside, cissogenin-3-O-β-D-oleandropyranoside and calogenin-3-O-α-L-diginopyranosyl-(1→4)-O-β-D-digitoxopyranoside, respectively.

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A pregnane ester oligoglycoside from Oxystelma esculentum

Cited by 11 publications

References 15 publications

The structure of velutinol A, an anti‐inflammatory compound with a novel pregnane skeleton

The structure of velutinol A, an anti‐inflammatory compound with a novel pregnane skeleton

A Complete Review on Oxystelma esculentum R. Br.

Three Pregnane Glycosides from Pergularia Pallida

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