A predictive model of minimally invasive bipolar fractional radiofrequency skin treatment

Berubé, Dany; Renton, Bradley; Hantash, Basil M.

doi:10.1002/lsm.20794

Cited by 30 publications

(41 citation statements)

References 20 publications

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“…Infiltrates have previously been shown to be effective at removing all discomfort associated with both needle insertion and FRF application without affecting the volume of thermal injuries. 4,5 In study Arm 1, the target temperature was low enough to avoid using infiltration. The treatment area extended from the nasolabial and melolabial folds medially, preauricular region laterally, and inferior margins of the submental and submandibular regions inferiorly, as previously described.…”

Section: Fractional Radiofrequency Treatmentmentioning

confidence: 99%

“…The control algorithm embedded in the system is adaptable, capable of reaching and maintaining a target dermal temperature in a wide range of clinically relevant dermal impedances. 4,5 Following informed verbal and written IRB consent, standardized preoperative digital photography was obtained. The skin was cleansed and anesthetized.…”

Section: Fractional Radiofrequency Treatmentmentioning

confidence: 99%

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Randomized, Blinded, 3-Arm Clinical Trial Assessing Optimal Temperature and Duration for Treatment With Minimally Invasive Fractional Radiofrequency

Alexiades

Berubé²

2015

Dermatologic Surgery

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Section: Fractional Radiofrequency Treatmentmentioning

confidence: 99%

Section: Fractional Radiofrequency Treatmentmentioning

confidence: 99%

Randomized, Blinded, 3-Arm Clinical Trial Assessing Optimal Temperature and Duration for Treatment With Minimally Invasive Fractional Radiofrequency

Alexiades

Berubé²

2015

Dermatologic Surgery

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“…Several treatment modalities are currently being used to address some of different aspects of the aging skin including peels, ablative and non-ablative lasers, focused ultrasound, RF-based devices as well as combined RF and optical energy modalities with each modality demonstrating varying degrees of success, safety and tolerability [1,3,[11][12][13][14][15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Clinical evaluation of the efficacy and safety of combined bipolar radiofrequency and optical energies vs. optical energy alone for the treatment of pigmented lesions and photo-damage in aging hands

Verner¹

2016

Glob Dermatol

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photo-aged skin ranging from the injection of neurotoxins and a multitude of filler products of varying compositions, chemical peels, to the use of energy-based modalities, such as focused ultrasound, RF, laser and light-based technologies. However, many of the modalities, particularly peels or ablative devices that are currently used to improve the typical signs of photoaging are limited by unwanted side effects that include post-inflammatory hyperpigmentation (PIH), prolonged downtime, low treatment tolerability and a risk for scarring [1][2][3][4]. Moreover rejuvenation of the hands has been associated with a higher risk for side effects than facial rejuvenation. Hand skin is thin and has few pilosebaceous units leading to a slow wound healing process and a higher risk for scarring. Thus, only low peel agent concentrations and low energies of energy-based devices can be used in this area.Ever since their inception, RF-based devices have become very popular in skin rejuvenation therapy due to the excellent treatment outcomes achievable coupled with minimal downtime, a favorable IntroductionNoninvasive skin rejuvenation therapy is becoming increasingly popular in aesthetic medicine, with innovative treatment modalities now also targeting the aging hands, a cosmetic indication that reaches beyond the more traditional aging face and décolletage indications. With noninvasive facial rejuvenation becoming very efficacious in recent years, a patient's true age is becoming apparent on the hands leading to the demand and need for efficacious treatment modalities for this area. Continued research has led to the steady development of ablative and nonablative energy-based devices that are being increasingly used for the cosmetic improvement of aging hands, which can be typically characterized by the development of dyschromias, solar lentigines, solar keratoses, fine telangiectasias, as well as a progressive loss of skin texture and skin atrophy resulting in varying degrees of wrinkling, fine lines and skin laxity that occur as a result of both intrinsic and extrinsic aging processes [1,2]. Topical agents, such as hydroquinone-based preparations and others, have long been employed to lighten and improve the cosmesis of pigmented lesions seen in aging skin; however, these topically applied preparations are not sufficiently effective in the treatment of solar lentigines (a very common complaint) and, moreover, they do not address other aspects photoaging, such as wrinkles, fine lines and skin laxity. AbstractBackground: Different treatment modalities are used for the treatment and aesthetic improvement of aging hands. This study evaluated the efficacy and safety of a novel technology, which combines bipolar radiofrequency (RF) and optical energies for the cosmetic treatment of aging hands.

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“…16,17 Other RF skin-tightening devices include those directly contacting the skin surface creating subablative/microablative effects. 18,19 Still other instruments use US waves that induce a molecular vibra-tion in a given tissue creating thermal coagulative focal necrosis. 20 And yet other tools are contactless ("no-touch") devices with panels that deliver IR thermal energy using frequencies and impedance variances based on tissue levels.…”

Section: Current Skin Rejuvenationmentioning

confidence: 99%

35 The Future of Rejuvenation Techniques for Aging Facial Skin

Truswell¹

2016

Lasers and Light, Peels and Abrasions

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In the absence of my trusty but rusty crystal ball, where will the future of skin rejuvenation take us? Just a few short years ago skin rejuvenation seemed limited to lay chemical peels, dermabrasion, "fruit acid" baths, and trauma. Today's landscape is much different.Let's begin with a review of the physiological changes associated with aging and the multitude of genetic and environmental factors that play key roles in the health and appearance of skin. We focus on the ability of skin to manufacture epidermis, collagen, and elastin; its ability to protect itself from sun and other environmental insults; how well its internal antioxidation processes ("rust") work; the degree of ongoing inflammation in the body; and how well our body processes glycogen (sugars). With aging, the outer skin layer (epidermis) thins, even though the number of cell layers remains unchanged. The number of melanocytes decreases, but the remaining melanocytes increase in size. Aging skin thus appears thinner, more pale, and translucent. Lentigines appear in sun-exposed areas. Connective tissue weakens (elastosis), reducing the skin's strength and elasticity and skin that has received an overdose of irradiation is easily identified. Dermal blood vessels become more fragile, leading to bruising and purpura. Sebaceous glands and sweat glands fail, resulting in increased dryness and itchiness. 1 At a cellular level, cell physiology takes complex pathways. Regeneration and senescence have in common with each other a set of signaling mediators called "cytokines," which include proteins, peptides, and glycoproteins. Cytokines can behave in both positive and negative ways. Bone-marrow-derived mesenchymal stem cells decline with advancing age. Research continues on ways to extract positive cytokines from stem cells and hopefully use them in aging therapy. 2 Inflammation continues to play a role in cellular, histological, and organ system aging and the role of anti-inflammatory strategies is a growing topic not only in dermatology but in other medical specialties. 3,4 Therefore, common-sense strategies are directed specifically to preventing, slowing down, and hopefully improving this inevitable process. Young and healthy-looking skin is a feature that is universally admired and considered attractive among humans. People seem obsessed with a youthful and healthy appearance. 5

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A predictive model of minimally invasive bipolar fractional radiofrequency skin treatment

Cited by 30 publications

References 20 publications

Randomized, Blinded, 3-Arm Clinical Trial Assessing Optimal Temperature and Duration for Treatment With Minimally Invasive Fractional Radiofrequency

Randomized, Blinded, 3-Arm Clinical Trial Assessing Optimal Temperature and Duration for Treatment With Minimally Invasive Fractional Radiofrequency

Clinical evaluation of the efficacy and safety of combined bipolar radiofrequency and optical energies vs. optical energy alone for the treatment of pigmented lesions and photo-damage in aging hands

35 The Future of Rejuvenation Techniques for Aging Facial Skin

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