A predictive index for determining the risk for presence of large esophageal, varices in pateints with cirrhosis

Role of Non-Invasive Methods to Predict the Presence of Gastro-Esophageal Varices among the Patients Present With Chronic Liver Disease

“…In the group of patients with cirrhosis, global diagnostic accuracy was 71%, and platelet count was isolated at the first step and prothrombin index at the 2nd step either for all EV or large EV Thus, platelet count appeared to be the best single marker of EV or large EV, since other markers added little information [35]. Platelet count has also been shown to be an independent marker in two other studies with multivariate analysis [28,36,37], reported the platelet count/spleen diameter ratio to be the only independent variable associated with presence of OV on multivariate analysis and identified a cut-off value of 909, giving a PPV of 96% and NPV of 100%. Sen et al, [38], found the platelet count-spleen diameter ratio of ≤650 as a sensitive non-invasive marker [Area under curve (AUC) of 0.81] in HCV related cirrhosis.…”