A practical treatise on the use of the microscope, including the different methods of preparing and examining animal, vegetable, and mineral structures

Quekett, John

doi:10.5962/bhl.title.56204

Cited by 4 publications

(2 citation statements)

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“…Some display commercial coverslip paper of the time and may have been purchased by Quekett, while others are likely to have been produced in-house by Quekett or his collaborators. In his treatise on the use of the microscope, Quekett describes dry and wet preparation methods for thin sections of bone, and examples of both are present in the collection today [ 58 ]. Exact anatomical location of our samples is unknown, although most seem to be taken along the diaphysis, based on seeing smooth endosteal surfaces with no trabeculae, except, as expected, in the two sloth species [ 59 ] and some of the marine mammals [ 60 ].…”

Section: Methodsmentioning

confidence: 99%

Secondary osteons scale allometrically in mammalian humerus and femur

et al. 2017

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Intra-cortical bone remodelling is a cell-driven process that replaces existing bone tissue with new bone tissue in the bone cortex, leaving behind histological features called secondary osteons. While the scaling of bone dimensions on a macroscopic scale is well known, less is known about how the spatial dimensions of secondary osteons vary in relation to the adult body size of the species. We measured the cross-sectional area of individual intact secondary osteons and their central Haversian canals in transverse sections from 40 stylopodal bones of 39 mammalian species (body mass 0.3–21 000 kg). Scaling analysis of our data shows that mean osteonal resorption area (negative allometry, exponent 0.23,R2 0.54,p<0.005) and Haversian canal area (negative allometry, exponent 0.31,R2 0.45,p<0.005) are significantly related to body mass, independent of phylogeny. This study is the most comprehensive of its kind to date, and allows us to describe overall trends in the scaling behaviour of secondary osteon dimensions, supporting the inference that the osteonal resorption area may be limited by the need to avoid fracture in smaller mammalian species, but the need to maintain osteocyte viability in larger mammalian species.

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Section: Methodsmentioning

confidence: 99%

Secondary osteons scale allometrically in mammalian humerus and femur

et al. 2017

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“…Drebbel started to produce similar microscopes with a biconvex eye lens and a plano-convex objective in 1619 and later passed them off as being of his own invention. 6,46,47 In 1624, Galileo developed a compound microscope and called it the "Occhialino," the "Little Eye." He used 2 convex lenses (as in a Keplerian system) instead of con- cave and convex lenses, as he had used in his initial telescope design.…”

Section: Development Of the Microscopementioning

confidence: 99%

Operating microscopes: past, present, and future

Uluç¹,

Kujoth²,

Başkaya³

2009

FOC

194

139

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The operating microscope is a fixture of modern surgical facilities, and it is a critically important factor in the success of many of the most complex and difficult surgical interventions used in medicine today. The rise of this key surgical tool reflects advances in understanding the principles of optics and vision that have occurred over centuries. The development of reading spectacles in the late 13th century led to the construction of early compound microscopes in the 16th and 17th centuries by Lippershey, Janssen, Galileo, Hooke, and others. Perhaps surprisingly, Leeuwenhoek's simple microscopes of this era offered improved performance over his contemporaries' designs. The intervening years saw improvements that reduced the spherical and chromatic aberrations present in compound microscopes. By the late 19th century, Carl Zeiss and Ernst Abbe ushered the compound microscope into the beginnings of the modern era of commercial design and production. The introduction of the microscope into the operating room by Nylén in 1921 initiated a revolution in surgical practice that gained momentum throughout the 1950s with multiple refinements, the introduction of the Zeiss OPMI series, and Kurze's application of the microscope to neurosurgery in 1957. Many of the refinements of the last 50 years have greatly improved the handling and practical operation of the surgical microscope, considerations which are equally important to its optical performance. Today's sophisticated operating microscopes allow for advanced real-time angiographic and tumor imaging. In this paper the authors discuss what might be found in the operating rooms of tomorrow.

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Microtome

2014

Laboratory Protocols in Applied Life Sciences

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A practical treatise on the use of the microscope, including the different methods of preparing and examining animal, vegetable, and mineral structures

Cited by 4 publications

References 0 publications

Secondary osteons scale allometrically in mammalian humerus and femur

Secondary osteons scale allometrically in mammalian humerus and femur

Operating microscopes: past, present, and future

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