A Practical Technique for Differentiation of Subepidermal Bullous Diseases

Woźniak, Katarzyna; Kazama, Tatsuo; Kowaléwski, Cezary

doi:10.1001/archderm.139.8.1007

Cited by 49 publications

(6 citation statements)

References 22 publications

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“…Additional tests may be considered according to clinical context and availability, and are listed in Table 1. 14,[22][23][24][25][26] 2 Therapeutic management…”

Section: Other Testsmentioning

confidence: 99%

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Management of bullous pemphigoid: the European Dermatology Forum consensus in collaboration with the European Academy of Dermatology and Venereology

et al. 2015

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Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or generalized bullous lesions. In up to 20% of affected patients, bullae may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. Our consensus for the treatment of bullous pemphigoid has been developed under the guidance of the European Dermatology Forum in collaboration with the European Academy of Dermatology and Venereology. It summarizes evidence-based and expert-based recommendations.

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“…Additional tests may be considered according to clinical context and availability, and are listed in Table 1. 14,[22][23][24][25][26] 2 Therapeutic management…”

Section: Other Testsmentioning

confidence: 99%

“…Additional tests may be considered according to clinical context and availability, and are listed in Table …”

Section: Initial Evaluation Of Bullous Pemphigoidmentioning

confidence: 99%

Management of bullous pemphigoid: the European Dermatology Forum consensus in collaboration with the European Academy of Dermatology and Venereology

et al. 2015

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“…In the case of EBA, collagen VII is found on the dermal side and thus immunoreactants will be visualized on the “floor” of the split. This is in contrast to bullous pemphigoid where the target antigen is most commonly on the epidermal side of the split and these reactants are seen on the “roof.” While serving as the gold standard, studies do show that up to 1/3 of patients have a negative membrane split evaluation presumably due to a low level of type VII collagen [ 13 , 14 ].…”

Section: Discussionmentioning

confidence: 99%

An 81-Year-Old Woman with Recalcitrant Blisters

Butler¹

2018

Dermatopathology

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“…The diagnosis of pemphigoid is based on the DIF finding of C3 with IgG (in 25% of cases) along the basement membrane zone in the skin. Pemphigoid gestationis is a self-limiting disease and can heal spontaneously after delivery [ 3 , 6 – 9 ]. The aim of the treatment is to prevent new blister formation and relieve pruritus.…”

Section: Discussionmentioning

confidence: 99%

Suspicion of pulmonary embolism during treatment of pemphigoid gestationis

Podolec-Rubis¹,

Wołek²,

Brzewski³

et al. 2013

pdia

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Pemphigoid gestationis (PG), first described in 1872 by Laws Milton, is a rare autoimmune bullous disease of pregnancy and puerperium. Pemphigoid gestationis has been estimated to occur in 1: 50 000 pregnancies and usually presents in the second or third trimester with exacerbation after partum. This disease is caused by circulating IgG1 immunoglobulin against hemidesmosomal protein bullous pemphigoid BP180 (BPAG2) type XVII collagen and less frequently BP230. We present a case of pemphigoid gestationis in primigravida with complications during treatment due to the suspicion of pulmonary embolism.

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A Practical Technique for Differentiation of Subepidermal Bullous Diseases

Cited by 49 publications

References 22 publications

Management of bullous pemphigoid: the European Dermatology Forum consensus in collaboration with the European Academy of Dermatology and Venereology

Management of bullous pemphigoid: the European Dermatology Forum consensus in collaboration with the European Academy of Dermatology and Venereology

An 81-Year-Old Woman with Recalcitrant Blisters

Suspicion of pulmonary embolism during treatment of pemphigoid gestationis

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