A Practical Consensus Guideline for the Integrative Treatment of Parkinson's Disease in Shanghai, China

Abstract

Integrative medicine, including traditional Chinese medicine (TCM), is a new concept in clinical practice for the treatment of neurodegenerative and most chronic diseases. However, integrative consensus or a guideline for the management of patients with Parkinson's disease (PD) is still lacking. The aim of this paper is to provide a review of experiences in clinical practice from Chinese neurologists and physicians (including TCM doctors) in Shanghai, China, and try to provide a clinical guideline for the treatment of the complex and progressive disease of PD with integrative medicine. We included the following treatments: common Western medication, surgery, TCM decoction and patent medicines, acupuncture and Tui na, Yoga, Tai chi chuan, hyperbaric oxygenation, rehabilitation, and other complementary and alternative medicines for the integrative management of the disease. Neurologists and physicians in Shanghai, China, and all over the world should pay attention to integrative medicine, which may be a good choice of treatment for PD.

A Computational Systems Pharmacology Approach to Investigate Molecular Mechanisms of Herbal Formula Tian-Ma-Gou-Teng-Yin for Treatment of Alzheimer’s Disease

“…Tian-Ma-Gou-Teng-Yin was prescribed for neurodegenerative diseases ( Chik et al, 2013 ) such as AD ( Liu et al, 2014 ; Lin et al, 2016 ) and Parkinson’s disease (PD) ( Pan et al, 2015 ), and also the prevention of hypertension ( Zhang et al, 2016 ). Upon previously detected disease modules, a network illustration of potential interactions between herbs and AD, hypertension related gene targets was constructed to speculate the synergistic effect of herb formula ( Figure 4 ).…”

Quantitative Evaluation of Chinese Herb Medicine in the Treatment of Sialorrhea and Frequent Nighttime Urination in Patients with Parkinson’s Disease

“…The diagnosis of PD was established when two of the main symptoms (bradykinesia, tremor, rigidity, and postural reflex abnormality) were presented [5]. The patients were at least 40 years of age and were evaluated in the middle of their levodopa dose cycle at maximal mobility (“on”) for the severity of parkinsonism.…”

Historical and cross-cultural perspectives on Parkinson’s disease

“…More specifically, studies designed to uncover the neurobiological basis of TCM "mind-body" practices suggest that they may exert their healing effects in PD by reducing inflammation and increasing blood flow, electrical signaling, and neurotransmitter bioavailability [16][17][18]. Recently a group of Chinese neurologists published consensus guidelines for the integrative treatment of PD in China [19]. They recommended specific and/or personalized TCM treatments (depending upon the expertise of the practitioner), in conjunction with Western pharmaceutical and surgical interventions.…”