2020
DOI: 10.1093/ajhp/zxaa051
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A practical approach to assess the hazardous exposure potential of investigational drugs

Abstract: Purpose A method to evaluate the hazardous exposure potential of investigational drugs was developed in order to comply with hazardous drug handling standards. Summary New nationwide standards require health-system pharmacies to recognize potential occupational risks and protect employees from any hazardous exposure. United States Pharmacopeia general chapter 800 (USP<800>) provides recommendations on handling p… Show more

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“…As such, viral-based in vivo therapies should be added to an institution's hazardous drug list due to the established and theoretical occupational risks for handling these therapies. 12,46 For example, the package insert of T-Vec indicates that health care personnel that are immunocompromised or pregnant should not handle, prepare, or administer the medication due to risk of developing a herpetic infection. 11 Onasemnogene abeparvovec recommends that caregivers practice safe handling of bodily fluids due to the risk of viral shedding.…”
Section: Development Of Institutional Handling Proceduresmentioning
confidence: 99%
“…As such, viral-based in vivo therapies should be added to an institution's hazardous drug list due to the established and theoretical occupational risks for handling these therapies. 12,46 For example, the package insert of T-Vec indicates that health care personnel that are immunocompromised or pregnant should not handle, prepare, or administer the medication due to risk of developing a herpetic infection. 11 Onasemnogene abeparvovec recommends that caregivers practice safe handling of bodily fluids due to the risk of viral shedding.…”
Section: Development Of Institutional Handling Proceduresmentioning
confidence: 99%