A potential use of metabolic profiles in the selection of superior cattle

Rowlands, G.J.; Payne, J. M.; Dew, SM; Manston, R.

doi:10.1136/vr.93.2.48

Cited by 9 publications

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“…In endemic regions, the partial signs are generally overlooked due to natural or vaccinal immunity [4]. The level of certain serum metabolites indicates the different disease conditions and degree of stress in the animal [5]. However, scanty literature is available on the effect of experimental FMD infection on blood and serum profile of cattle, which is important for formulating the ameliorative measures to reduce the biotic stress on the animal due to the infection.…”

Section: Introductionmentioning

confidence: 99%

Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus

et al. 2020

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Background and Aim: Foot-and-mouth disease (FMD) is an acute viral infection affecting cloven-hoofed animals causing vesicular erosions in the oral cavity and interdigital space. The present study was undertaken to ascertain the time-dependent changes in clinical, hematological, and biochemical profiles in different breeds of cattle following experimental infection. Materials and Methods: The animals were inoculated with 1.0×104 50% bovine tongue infectious dose (BTID50) by intradermolingual route. Clinical signs were observed, and blood/serum samples were collected at different time intervals. Results: The white blood cell count declined sharply on days 7-13 and recovered on day 14 post-FMD infection. Biochemical analysis of serum markers for vital organ profile revealed no marked damage. However, a significant increase in blood urea nitrogen (BUN) value indicated pre-renal azotemia. Transient hyperthyroidism was indicated by the rise in T3 and T4 that can be correlated with a decrease in triglyceride and total cholesterol levels. In the cardiac damage assessment study, a distinct breed difference was observed wherein Malnad Gidda calves showed no cardiac damage. Conclusion: Except thyroid profile, BUN, and creatine kinase-myocardial band, all other serum biochemical parameters showed no significant abnormalities, whereas lymphopenia is the only hematological change and it is suggested that effective ameliorative measures should be targeted mainly on the feed/water intake, thyroid gland, and the level of lymphocytes.

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Section: Introductionmentioning

confidence: 99%

Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus

et al. 2020

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“…11,18 The original objectives of the CMPT were: (a) to secure high yield at minimum costs, (b) to demonstrate the interrelationships of blood constituents with nutrition, productivity and fertility, (c) to monitor metabolic health of the herd, (d) to help diagnosis metabolic problems and production diseases, and (e) to identify metabolically superior cows. 10,19 The original CMPT measured 13 different blood constituents that included packed cell volume (PCV), haemoglobulin (Hb), glucose, blood urea nitrogen (BUN), total protein (TP), albumin (Ab), calcium (Ca), phosphorus (P), magnesium (Mg), potassium (K), sodium (Na), copper (Cu) and ferrous (Fe). The MPT is usually performed on blood samples at four time periods relative to calving (dry, puerperium, peak lactation and mid lactation) and measuring selected blood metabolites.…”

Section: Discussionmentioning

confidence: 99%

Relationship Between Blood Metabolic Profiles and Milk Yield Associated With Parity and Stage of Lactation in Crossbred Dairy Cows in Bangladesh

Naher¹,

Samad²,

Siddiki³

et al. 2019

JVMOHR

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Background: Cattle cross-breeding program has been launched throughout Bangladesh but this program has still focused mainly on biological rather than economic evaluation. Currently, 30000 dairy farms with mainly cross-bred cows are in operation throughout the country and this intensive dairy farming system with high milk yielding dairy cows is supposed to be associated with high incidence of sub-clinical nutritional and metabolic diseases. Objectives: The objective of this study was to detect the relationship between major blood metabolic profiles and milk yield associated with parity and stage of lactation in cross-bred dairy cows. Materials and Methods: Blood samples of 220 apparently healthy lactating cross-bred dairy cows (HF x L, n = 190; SH x L, n = 20 and JS x L, n = 10) of 10 dairy herds were collected for metabolic profile test (MPT) in Bangladesh during the period from July to November 2016. The major metabolic profiles which are associated with milk fever (calcium, phosphorus & magnesium) and ketosis (glucose) were considered in this study. These biochemical parameters were estimated to detect the influence of risk factors including herds, breeds, parities and lactation age of cross-bred lactating dairy cows by using the commercial kits in spectrophotometer method. Results: The evaluation of the biochemical constituents of 220 cross-bred lactating dairy cows revealed that 30% (n = 66) had hypocalcaemia and 20.45% (n = 45) had hypoglycemia. Significantly lower levels of average calcium (7.93 ± 0.36 mg/dl; p < 0.024) and glucose (43.44 ± 3.63 mg/dl; p < 0.0001) values were recorded in HF x L cross-bred dairy herd of BAUDF, Mymensingh in comparison to other investigated nine dairy herds. The highest milk yield was recorded at 7th parity (16 +- 0.91 liter / day) and 1st week of lactation (17.33 +- 1.09 liter / day) were associated with low mean calcium (8.09 +- 0.85 mg / dl; 6.68 +- 0.13 mg/dl) and glucose (36.45 +- 7.67 mg/dl; 32.31 +- 3.90 mg / dl) levels in comparison to the respective values of different parity and lactation weeks. Conclusions: A relationship between blood metabolic profiles and milk yield associated with herd, breed, parity and lactation stages was recorded in lactating crossbred dairy cows. The evaluation of blood metabolites at different stages of lactation cycle especially at transition period is required to detect the nutritional and metabolic health for optimum milk production and to achieve maximum reproductive potential of high yielding dairy cattle. The readily available milk samples could be used as a biological fluid to monitor the health and nutritional status of dairy cows by using mid-infrared (MIR) spectroscopy method to prevent sub-clinical metabolic disorders. Therefore, well developed laboratories with necessary equipment, test kits and reagent should be provided to perform MPT in both the blood and milk samples for practical uses. Keywords: Compton metabolic profile test, Metabolic profile, Lactating cross-bred cows, Calcium, Phosphorus, Magnesium, Glucose, Parity, Lactation stages

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“…Likewise, in the Paraguayan cattle in South Africa (Otto et al., 1992) and Angoni cattle in Mozambique (Otto et al., 2000), the mean concentration of total protein appeared to be higher than the range given for the cattle (85.0 g/l in Paraguayan cattle and 83.8 g/l in Angoni cattle, respectively). Several investigators have mentioned that the plasma protein profile of a particular individual is relatively constant over a considerable length of time (Rowlands et al., 1973; Anderson et al., 1987; Knowles et al., 2000; Coppo, 2004). This constancy is apparently controlled genetically.…”

Section: Discussionmentioning

confidence: 99%

Blood Biochemical Profiles of Thai Indigenous and Simmental × Brahman Crossbred Cattle in the Central Thailand

Boonprong¹,

Sribhen

Choothesa

et al. 2007

Journal of Veterinary Medicine Series A

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Plasma biochemical profiles were studied in 112 mature (3 to 5-year-old) healthy cattle comprised of 61 Thai indigenous and 51 Simmental x Brahman crossbred male and cyclic female cattle at Nongkwang (Central Thailand) Livestock Research and Breeding Center, Thailand. Data were analysed for the effect of breed and sex. The results showed that the plasma glucose and gamma-glutamyl transferase (GGT) in the two breeds were significantly (P < 0.05) different. Furthermore, the urea, creatinine, albumin, total protein, aspartate amino transferase (AST), alanine amino transferase (ALT) and alkaline phosphatase (ALP) levels in Thai indigenous were significantly (P < 0.01) higher than in crossbred cattle. However, creatine kinase did not significantly differ in crossbred and indigenous animals. A sex difference was found in glucose level with male Thai indigenous having significantly higher levels (P < 0.05) than the other three groups. Plasma urea concentration in male crossbred cattle was lower than in the other groups (P < 0.05). Female crossbred cattle had significantly (P < 0.05) lower plasma creatinine levels than the other animals. Furthermore, levels of albumin in male and total protein in female crossbred were the lowest (P < 0.05) among the groups. The AST, ALT, ALP and GGT levels were significantly (P < 0.05) different between male and female. Female crossbred cattle had the lowest (P < 0.05) AST and GGT levels, whereas lowest (P < 0.05) ALT and ALP concentration was determined in male individuals of these breeds.

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A potential use of metabolic profiles in the selection of superior cattle

Cited by 9 publications

References 0 publications

Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus

Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus

Relationship Between Blood Metabolic Profiles and Milk Yield Associated With Parity and Stage of Lactation in Crossbred Dairy Cows in Bangladesh

Blood Biochemical Profiles of Thai Indigenous and Simmental × Brahman Crossbred Cattle in the Central Thailand

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