Humans extract information from the key features of the physical word, namely space and time. However, while much is known about the neural processing of visuospatial patterns, there is little information on the hierarchical brain mechanisms underlying conscious recognition of auditory sequences extended over time and their associated prediction errors. Using magnetoencephalography (MEG), we studied the brain activity of 83 participants during recognition of original and varied auditory sequences. Results showed a network comprising auditory, ventro-medial prefrontal and inferior temporal cortices, hippocampus, and medial cingulate gyrus underlying sequence processing. The hierarchical pathway from auditory cortex to hippocampus and ventro-medial prefrontal cortex was associated with both originals and variations, but its temporal dynamics crucially differed. Recognition of original versus varied sequences elicited stronger gamma power. Our results complement the knowledge on neural processing of visuospatial patterns by providing the hierarchical brain mechanisms underlying auditory, temporal sequence recognition.